PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21052098-4 2011 We demonstrated that Ad-ING4 plus CDDP induced synergistic growth inhibition, enhanced apoptosis, and had an additive effect on upregulation of Fas, Bax, Bak, cleaved Bid, cleaved caspase-8, caspase-9, caspase-3 and cleaved PARP, and on downregulation of Bcl-2 and Bcl-X(L) in SMMC-7721 hepatocarcinoma cells. smmc 277-281 inhibitor of growth family member 4 Homo sapiens 24-28 21052098-5 2011 Moreover, Ad-ING4 plus CDDP synergistically suppressed in vivo SMMC-7721 hepatocarcinoma subcutaneous (s.c.) xenografted tumor growth and reduced tumor vessel CD34 expression and microvessel density (MVD) in athymic nude mice. smmc 63-67 inhibitor of growth family member 4 Homo sapiens 13-17 27421660-6 2016 Ad-ING4-PTEN cooperatively inhibited cell growth, stimulated apoptosis, and suppressed invasion in both HCC cells, and regulated cell cycle in SMMC-7721. smmc 143-147 inhibitor of growth family member 4 Homo sapiens 3-7 21052098-3 2011 In this study, we explored the combined effect of adenovirus-mediated ING4 (Ad-ING4) gene transfer plus chemotherapy drug cisplatin (CDDP) on SMMC-7721 human hepatocarcinoma cells in vitro and in vivo, and its underlying mechanism. smmc 142-146 inhibitor of growth family member 4 Homo sapiens 70-74 21052098-3 2011 In this study, we explored the combined effect of adenovirus-mediated ING4 (Ad-ING4) gene transfer plus chemotherapy drug cisplatin (CDDP) on SMMC-7721 human hepatocarcinoma cells in vitro and in vivo, and its underlying mechanism. smmc 142-146 inhibitor of growth family member 4 Homo sapiens 79-83