PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23158190-7	2012	Unique from other targeted therapies, withanolides suppressed RET and Akt phosphorylation and protein expression (in a concentration- and time-dependent manner) as well as mTOR activity and translational activity of 4E-BP1 and protein synthesis mediated by p70S6kinase activation at IC(50) concentrations.	Withanolides	38-50	ret proto-oncogene	Homo sapiens	62-65	
23158190-0	2012	Novel withanolides target medullary thyroid cancer through inhibition of both RET phosphorylation and the mammalian target of rapamycin pathway.	Withanolides	6-18	ret proto-oncogene	Homo sapiens	78-81	
23158190-3	2012	We hypothesize that these withanolides uniquely inhibit RET phosphorylation and the mammalian target of rapamycin (mTOR) pathway in MTC cells as a mechanism of antiproliferation and apoptosis.	Withanolides	26-38	ret proto-oncogene	Homo sapiens	56-59