PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23158190-7 2012 Unique from other targeted therapies, withanolides suppressed RET and Akt phosphorylation and protein expression (in a concentration- and time-dependent manner) as well as mTOR activity and translational activity of 4E-BP1 and protein synthesis mediated by p70S6kinase activation at IC(50) concentrations. Withanolides 38-50 eukaryotic translation initiation factor 4E binding protein 1 Homo sapiens 216-222