PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
8104954-8	1993	In patients with Paget"s disease, B-ALP was highly correlated with T-ALP (r2 = 0.94; P < 0.001), and the decrease in its serum level was larger than that in T-ALP after treatment with the bisphosphonate pamidronate (-58% vs. -43%; P < 0.03).	Diphosphonates	191-205	ATHS	Homo sapiens	36-39	
12109626-9	2002	In conclusion, we found that different bisphosphonates, currently used or tested in various clinical conditions, transiently stimulated the growth of preosteoblastic cells and thereafter increased their differentiation according to sequential events (type I collagen synthesis first, then ALP activity to a lesser extent).	Diphosphonates	39-54	ATHS	Homo sapiens	289-292	
9761247-11	1998	The Tandem-MP Ostase bone ALP assay demonstrated increased concentrations of serum bone ALP in conditions where bone metabolism is increased and showed a rapid, temporal decrease in serum bone ALP in Paget disease patients on bisphosphonate therapy.	Diphosphonates	226-240	ATHS	Homo sapiens	26-29	
9761247-11	1998	The Tandem-MP Ostase bone ALP assay demonstrated increased concentrations of serum bone ALP in conditions where bone metabolism is increased and showed a rapid, temporal decrease in serum bone ALP in Paget disease patients on bisphosphonate therapy.	Diphosphonates	226-240	ATHS	Homo sapiens	88-91	
9761247-11	1998	The Tandem-MP Ostase bone ALP assay demonstrated increased concentrations of serum bone ALP in conditions where bone metabolism is increased and showed a rapid, temporal decrease in serum bone ALP in Paget disease patients on bisphosphonate therapy.	Diphosphonates	226-240	ATHS	Homo sapiens	88-91	
8849398-13	1996	administration of bisphosphonates, the decrease of BALP was more marked than that of total ALP (median: -54% versus -41%; P < 0.05).	Diphosphonates	18-33	ATHS	Homo sapiens	52-55	
26037791-13	2015	After starting treatment with bisphosphonate, there was moderate to strong correlation with disease activity with all markers except bone ALP (correlation coefficients ranging from 0.43 to 0.70).	Diphosphonates	30-44	ATHS	Homo sapiens	138-141	
25002880-6	2014	Treatment with bisphosphonates has led to remission of disease: normalization of ALP values in 90%, documented by the scintigraphy of control.	Diphosphonates	15-30	ATHS	Homo sapiens	81-84	
21552192-6	2011	In fact, the patients treated with bisphosphonates had significantly lower levels both of pain and total ALP.	Diphosphonates	35-50	ATHS	Homo sapiens	105-108