PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22996291-2	2013	Zoledronic acid (ZA) is a bisphosphonate known to upregulate the expression of TRAIL on human gammadelta T cells.	Diphosphonates	26-40	TNF superfamily member 10	Homo sapiens	79-84	
30120241-0	2018	Author Correction: Bisphosphonate enhances TRAIL sensitivity to human osteosarcoma cells via death receptor 5 upregulation.	Diphosphonates	19-33	TNF superfamily member 10	Homo sapiens	43-48	
19577359-7	2010	In conclusion, zoledronic acid enhanced the TRAIL-to-OPG ratio in TRAIL-sensitive MDA-MB-231 cells, indicating that the TRAIL/OPG cytokine system is a bisphosphonate-responsive target in breast cancer.	Diphosphonates	151-165	TNF superfamily member 10	Homo sapiens	44-49	
21297379-0	2011	Bisphosphonate enhances TRAIL sensitivity to human osteosarcoma cells via death receptor 5 upregulation.	Diphosphonates	0-14	TNF superfamily member 10	Homo sapiens	24-29	
21297379-4	2011	The purpose of this study was to determine the effects of bisphosphonates on TRAIL-resistant MG 63 human osteosarcoma cells.	Diphosphonates	58-73	TNF superfamily member 10	Homo sapiens	77-82	
21297379-5	2011	The cells showed no response to TRAIL alone; however, pre-treatment with bisphosphonates significantly increased TRAIL-mediated apoptosis and cellular activation of caspase-3.	Diphosphonates	73-88	TNF superfamily member 10	Homo sapiens	113-118	
21297379-6	2011	Bisphosphonates significantly induced mRNA and protein expression of the TRAIL receptor, DR5.	Diphosphonates	0-15	TNF superfamily member 10	Homo sapiens	73-78	
21297379-7	2011	Bisphosphonates induced protein unprenylation in MG 63 cells; in addition, co-treatment with TRAIL also significantly increased protein unprenylation.	Diphosphonates	0-15	TNF superfamily member 10	Homo sapiens	93-98	
21297379-9	2011	This is the first study to demonstrate that bisphosphonates markedly enhanced TRAIL-induced apoptosis in human osteosarcoma cells.	Diphosphonates	44-59	TNF superfamily member 10	Homo sapiens	78-83	
21297379-10	2011	These findings suggest that bisphosphonates may be a new and effective anticancer treatment with TRAIL proteins for TRAIL-resistant cancer cells.	Diphosphonates	28-43	TNF superfamily member 10	Homo sapiens	97-102	
21297379-10	2011	These findings suggest that bisphosphonates may be a new and effective anticancer treatment with TRAIL proteins for TRAIL-resistant cancer cells.	Diphosphonates	28-43	TNF superfamily member 10	Homo sapiens	116-121	
19577359-7	2010	In conclusion, zoledronic acid enhanced the TRAIL-to-OPG ratio in TRAIL-sensitive MDA-MB-231 cells, indicating that the TRAIL/OPG cytokine system is a bisphosphonate-responsive target in breast cancer.	Diphosphonates	151-165	TNF superfamily member 10	Homo sapiens	66-71	
19577359-7	2010	In conclusion, zoledronic acid enhanced the TRAIL-to-OPG ratio in TRAIL-sensitive MDA-MB-231 cells, indicating that the TRAIL/OPG cytokine system is a bisphosphonate-responsive target in breast cancer.	Diphosphonates	151-165	TNF superfamily member 10	Homo sapiens	66-71