PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16520738-3	2006	Buddlejasaponin IV (2.5-10 microM) reduced lipopolysaccaride (LPS (1 microg ml(-1)))-induced levels of iNOS and COX-2 at the protein levels, and iNOS, COX-2, TNF-alpha, interleukin (IL)-1beta and IL-6 mRNA expression in RAW 264.7 macrophages in a concentration-dependent manner, as determined by Western blotting and RT-PCR, respectively.	lipopolysaccaride	43-60	tumor necrosis factor	Homo sapiens	158-167	
17451682-0	2007	HIF-1alpha expression in response to lipopolysaccaride mediates induction of hepatic inflammatory cytokine TNFalpha.	lipopolysaccaride	37-54	tumor necrosis factor	Homo sapiens	107-115	
25274725-5	2014	Contrary to expectation, we predicted and then experimentally confirmed that in response to lipopolysaccaride, TNF does not have an autocrine function in amplifying the NFkappaB response, although it plays a potent paracrine role in neighboring cells.	lipopolysaccaride	92-109	tumor necrosis factor	Homo sapiens	111-114	
17692969-12	2008	TNF-alpha and sphingosine, that are increased because of the enhanced lipopolysaccaride concentration due to altered gut permeability, may play a pathophysiological role in the development of this myopathy.	lipopolysaccaride	70-87	tumor necrosis factor	Homo sapiens	0-9	
15261284-2	2004	Many of these compounds show low nanomolar activity against lipopolysaccaride (LPS)-induced TNF-alpha production in THP-1 cells.	lipopolysaccaride	60-77	tumor necrosis factor	Homo sapiens	92-101	
16435585-5	2005	The amount of tumor necrosis factor (TNF)-alpha, interleukin (IL)-1alpha, IL-1beta, IL-6, and IL-8 in PBMC culture supernatant was significantly increased in the lipopolysaccaride (LPS)- or desferrioxamine (DFX)-treated cells compared with unstimulated cells.	lipopolysaccaride	162-179	tumor necrosis factor	Homo sapiens	14-47	
15569326-8	2004	After lipopolysaccaride stimulation, monocyte production of IL-1beta, TNF-alpha, and IL-6 in ARF patients was reduced by 41%, 84%, and 45%, respectively, compared to healthy subjects (P < 0.01 in each case), and similarly reduced compared to CKD and ESRD patients, and were similar to CRIT ILL patients.	lipopolysaccaride	6-23	tumor necrosis factor	Homo sapiens	70-79