PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20814160-2 2010 Low activities for dealkylation of ethoxyresorufin and pentoxyresorufin were seen in recombinant monkey mfCYP3A4 and mfCYP3A5 and in recombinant human CYP3A4 and CYP3A5 expressed in bacterial membranes. ethoxyresorufin 35-50 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 106-112 15037195-7 2004 CYP1A2 and CYP3A4 induction was determined by measuring 7-ethoxyresorufin-O-deethylation activity and 6beta-hydroxytestosterone formation, respectively. ethoxyresorufin 56-73 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 11-17 8093105-12 1994 In human liver microsomes, antibody inhibition and furafylline inhibition showed that ethoxyresorufin and methoxyresorufin were metabolised mainly by CYP1A2, whilst benzyloxyresorufin metabolism was due mainly to the CYP3A subfamily but also involved CYP1A2 and CYP2A6. ethoxyresorufin 86-101 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 217-222 11701226-6 2001 Testosterone, chlorzoxazone, and ethoxyresorufin were used as selective substrates for CYP3A, CYP2E1 and CYP1A1/1A2, respectively. ethoxyresorufin 33-48 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 87-92 10877007-6 2000 Losartan and irbesartan inhibited CYP1A2- and CYP3A4-associated activities (ethoxyresorufin O-deethylation and testosterone 6beta-hydroxylation) with relatively weak affinities (IC50 values between 200 microM and 500 microM). ethoxyresorufin 76-91 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 46-52 10064566-6 1999 The possibility that CYP3A4 metabolizes 7-ethoxyresorufin was excluded because there was no correlation between intestinal CYP3A4 catalytic and EROD activity, and cDNA-expressed human CYP3A4 exhibited no EROD activity. ethoxyresorufin 40-57 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 21-27 12818727-5 2003 Ethoxyresorufin, coumarin, benzoxyresorufin, chlorzoxazone, testosterone and lauric acid were used as selective substrates for CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2B6, CYP2E1, CYP3A4 and CYP4A, respectively. ethoxyresorufin 0-15 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 175-181