PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33717236-3	2021	The aim of the present study was to investigate the role of IL-1beta in paclitaxel sensitivity of NSCLC cells and elucidate the underlying mechanism.	Paclitaxel	72-82	interleukin 1 alpha	Homo sapiens	60-68	
9169462-1	1997	Role of protein kinase C. Paclitaxel can induce tumor necrosis factor (TNF) and interleukin-1 gene expression, similar to lipopolysaccharides.	Paclitaxel	26-36	interleukin 1 alpha	Homo sapiens	80-93	
35163066-4	2022	In the present study, we demonstrated, by using both primary epidermal keratinocytes (NHEK) and a 3D epidermis model, that paclitaxel impairs different cellular processes: paclitaxel increased the release of IL-1alpha, IL-6, and IL-8 inflammatory cytokines, produced reactive oxygen species (ROS) release and apoptosis, and reduced the endothelial tube formation in the dermal microvascular endothelial cells (HDMEC).	Paclitaxel	123-133	interleukin 1 alpha	Homo sapiens	208-217	
35163066-4	2022	In the present study, we demonstrated, by using both primary epidermal keratinocytes (NHEK) and a 3D epidermis model, that paclitaxel impairs different cellular processes: paclitaxel increased the release of IL-1alpha, IL-6, and IL-8 inflammatory cytokines, produced reactive oxygen species (ROS) release and apoptosis, and reduced the endothelial tube formation in the dermal microvascular endothelial cells (HDMEC).	Paclitaxel	172-182	interleukin 1 alpha	Homo sapiens	208-217	
33717236-5	2021	Subsequently, Cell Counting Kit-8 assay and flow cytometry revealed that IL-1beta weakened the sensitivity of A549 cells to paclitaxel.	Paclitaxel	124-134	interleukin 1 alpha	Homo sapiens	73-81	
33717236-7	2021	Thus, the results revealed that IL-1beta reduced the sensitivity to paclitaxel in A549 cells by promoting autophagy and suggested that IL-1beta may be of value for improving the therapeutic efficacy of paclitaxel chemotherapy in NSCLC.	Paclitaxel	68-78	interleukin 1 alpha	Homo sapiens	32-40	
33717236-7	2021	Thus, the results revealed that IL-1beta reduced the sensitivity to paclitaxel in A549 cells by promoting autophagy and suggested that IL-1beta may be of value for improving the therapeutic efficacy of paclitaxel chemotherapy in NSCLC.	Paclitaxel	68-78	interleukin 1 alpha	Homo sapiens	135-143	
33717236-7	2021	Thus, the results revealed that IL-1beta reduced the sensitivity to paclitaxel in A549 cells by promoting autophagy and suggested that IL-1beta may be of value for improving the therapeutic efficacy of paclitaxel chemotherapy in NSCLC.	Paclitaxel	202-212	interleukin 1 alpha	Homo sapiens	32-40	
33717236-7	2021	Thus, the results revealed that IL-1beta reduced the sensitivity to paclitaxel in A549 cells by promoting autophagy and suggested that IL-1beta may be of value for improving the therapeutic efficacy of paclitaxel chemotherapy in NSCLC.	Paclitaxel	202-212	interleukin 1 alpha	Homo sapiens	135-143	
32998017-10	2020	SIGNIFICANCE: Paclitaxel could protect against LPS-induced AKI via the regulation of lnc-MALAT1/miR-370-3p/HMGB1 axis and the expression of TNF-alpha, IL-6 and IL-1beta, revealing that paclitaxel might act as a therapy drug in reducing sepsis-associated AKI.	Paclitaxel	14-24	interleukin 1 alpha	Homo sapiens	160-168	
31993881-5	2020	In this study, we observed that Taxol treatment caused pyroptotic cell death, along with activation of Caspase-1 and maturation of IL-1beta, as well as cleavage of GSDMD, which is the canonical pyroptosis executor.	Paclitaxel	32-37	interleukin 1 alpha	Homo sapiens	131-139