PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26462028-4 2015 Blocking TGF-beta signaling with the TGF-beta type I receptor kinase (ALK5) inhibitor, EW-7197, suppresses paclitaxel-induced EMT and CSC properties such as mammosphere-forming efficiency (MSFE), aldehyde dehydrogenase (ALDH) activity, CD44+/CD24- ratio, and pluripotency regulators (Oct4, Nanog, Klf4, Myc, and Sox2). Paclitaxel 107-117 Nanog homeobox Homo sapiens 290-295 34610216-7 2021 RESULTS: The expression levels of C-MYC and NANOG were significantly higher in paclitaxel-resistant PC-3 cells compared to the parental PC-3 cells. Paclitaxel 79-89 Nanog homeobox Homo sapiens 44-49 32986398-0 2020 Internal Oligoguanidinium Transporter: Mercury Free Scalable Synthesis, Improvement of Cellular Localization, Endosomal Escape, Mitochondrial Localization and Conjugation with Antisense Morpholino for NANOG Inhibition to Induce Chemosensitisation of Taxol in MCF-7 Cells. Paclitaxel 250-255 Nanog homeobox Homo sapiens 201-206 32986398-8 2020 To the best of our knowledge, this is the first report to illustrate that the IGT-PMO-mediated NANOG inhibition increases the therapeutic potential of taxol and induces G0-G1 arrest in cancer cells to prevent the cancer progression. Paclitaxel 151-156 Nanog homeobox Homo sapiens 95-100 32779438-10 2020 Overexpression of GATA5 also promoted Paclitaxel to inhibit expression of reprogramming genes, such as Nanog, EpCAM, c-Myc and Sox2 in Bel7402 and PLC/PRF/5 cells. Paclitaxel 38-48 Nanog homeobox Homo sapiens 103-108 31867270-10 2019 In order to test this, we generated a paclitaxel-resistant TNBC cell line which demonstrated an elevated level of eIF4A along with increased levels of cancer stemness markers (ALDH activity and CD44), pluripotency transcription factors (SOX2, OCT4, and NANOG) and drug transporters (ABCB1, ABCG2, and ABCC1). Paclitaxel 38-48 Nanog homeobox Homo sapiens 253-258 33599261-0 2021 Nanog-mediated stem cell properties is critical for MBNL3 associated paclitaxel resistance of ovarian cancer. Paclitaxel 69-79 Nanog homeobox Homo sapiens 0-5 33599261-8 2021 This study suggests the MBNL3-Nanog axis is a therapeutic target for the treatment of PTX-resistance in ovarian cancer management. Paclitaxel 86-89 Nanog homeobox Homo sapiens 30-35 32254809-5 2019 The results of the role of autophagy in the sensitivity of chemotherapeutic PTX to glioma cells showed that the stemness-associating genes (SOX2, POU5F1 and NANOG) of live glioma cells increased in the presence of PTX, while they dropped sharply with the combination including CQ. Paclitaxel 76-79 Nanog homeobox Homo sapiens 157-162 23095773-2 2012 METHODS: The expression of NANOG was evaluated in 6 ovarian carcinoma cell lines, paclitaxel-resistant SKOV3 cells, and SKOV3 spheroid cells with semiquantitative reverse transcription-polymerase chain reaction and Western blotting. Paclitaxel 82-92 Nanog homeobox Homo sapiens 27-32 23095773-6 2012 The mRNA level of NANOG was increased in the paclitaxel-resistant SKOV3 cells and SKOV3 spheroid cells compared with that in the SKOV3 cells. Paclitaxel 45-55 Nanog homeobox Homo sapiens 18-23