PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12084458-9	2002	The enzyme uridine-cytidine monophosphate kinase (UMPK) is an essential and rate-limiting enzyme in 5-FU activation while dihydropyrimidine dehydrogenase (DPD) is a catabolic enzyme that inactivates 5-FU.	Fluorouracil	100-104	uridine-cytidine kinase 2	Homo sapiens	50-54	
21449674-4	2011	RESULTS: Of the 24 genes analyzed, 13 produced significant changes on the phenotype of sensitivity to 5-FU (DHFR, DPYS, DTYMK, DUT, FPGS, GGH, NME1, NT5C, RRM1, TYMS, UCK2, UNG and UMPS).	Fluorouracil	102-106	uridine-cytidine kinase 2	Homo sapiens	167-171	
12084458-9	2002	The enzyme uridine-cytidine monophosphate kinase (UMPK) is an essential and rate-limiting enzyme in 5-FU activation while dihydropyrimidine dehydrogenase (DPD) is a catabolic enzyme that inactivates 5-FU.	Fluorouracil	100-104	uridine-cytidine kinase 2	Homo sapiens	11-48	
12084458-9	2002	The enzyme uridine-cytidine monophosphate kinase (UMPK) is an essential and rate-limiting enzyme in 5-FU activation while dihydropyrimidine dehydrogenase (DPD) is a catabolic enzyme that inactivates 5-FU.	Fluorouracil	199-203	uridine-cytidine kinase 2	Homo sapiens	11-48	
12084458-9	2002	The enzyme uridine-cytidine monophosphate kinase (UMPK) is an essential and rate-limiting enzyme in 5-FU activation while dihydropyrimidine dehydrogenase (DPD) is a catabolic enzyme that inactivates 5-FU.	Fluorouracil	199-203	uridine-cytidine kinase 2	Homo sapiens	50-54	
12084458-10	2002	Alterations in UMPK and DPD may therefore explain failure of 5-FU response in the absence of alterations in TS or p53.	Fluorouracil	61-65	uridine-cytidine kinase 2	Homo sapiens	15-19	
195585-4	1977	During the development of tumour-cell resistance to 5-fluorouracil or 5-fluorouridine in vivo there was an early differential increase in the activity of a low-affinity (high-Km) uridine kinase isoenzyme, as measured in cell extracts, and a 7-fold increase in the Km values for the uptake of both uridine and 5-fluorouridine into the intact resistant cells.	Fluorouracil	52-66	uridine-cytidine kinase 2	Homo sapiens	179-193