PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28724889-0 2017 Aptamer-mediated survivin RNAi enables 5-fluorouracil to eliminate colorectal cancer stem cells. Fluorouracil 39-53 baculoviral IAP repeat-containing 5 Mus musculus 17-25 28724889-4 2017 When combined with the conventional chemotherapeutic agents, the aptamer-guided survivin RNAi was able to enhance the sensitivity towards 5-FU or oxaliplatin in colorectal cancer stem cells, increase apoptosis, inhibit tumour growth and improve the overall survival of mice bearing xenograft colorectal cancer. Fluorouracil 138-142 baculoviral IAP repeat-containing 5 Mus musculus 80-88 20159707-0 2010 [Survivin antisense oligodeoxynucleotides inhibits the proliferation of hepatocellular carcinoma cells and enhances 5-FU sensitivity]. Fluorouracil 116-120 baculoviral IAP repeat-containing 5 Mus musculus 1-9 26647806-0 2016 Smad4 sensitizes colorectal cancer to 5-fluorouracil through cell cycle arrest by inhibiting the PI3K/Akt/CDC2/survivin cascade. Fluorouracil 38-52 baculoviral IAP repeat-containing 5 Mus musculus 111-119 22261621-5 2012 An in vivo nude mouse xenograft assay was performed to assess the effects of Survivin knockdown on regulation of the sensitivity of SGC7901 cells to irradiation, cisplatin or 5-FU treatment. Fluorouracil 175-179 baculoviral IAP repeat-containing 5 Mus musculus 77-85 22261621-7 2012 The same is true for cisplatin- and 5-FU-treated tumor cells, ie, colony formation and cell viability of the survivin-knocked down SGC7901 cells were reduced, while apoptosis was induced compared with the control cells. Fluorouracil 36-40 baculoviral IAP repeat-containing 5 Mus musculus 109-117 22261621-9 2012 CONCLUSIONS: Knockdown of survivin expression enhanced sensitivity of gastric cancer cells to radiation, cisplatin and 5-FU treatment in vitro and in nude mice. Fluorouracil 119-123 baculoviral IAP repeat-containing 5 Mus musculus 26-34 20159707-1 2010 OBJECTIVE: To investigate the inhibitory effect of survivin antisense oligodeoxynuleotides (ASODN) mediated by polyethylenimine (PEI) on hepatocelluar carcinoma SMMC-7721 cell proliferation and its effect on chemosensitivity to 5-FU in tumor-bearing mice. Fluorouracil 228-232 baculoviral IAP repeat-containing 5 Mus musculus 51-59