PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29636622-0 2018 miR-206 regulates 5-FU resistance by targeting Bcl-2 in colon cancer cells. Fluorouracil 18-22 microRNA 206 Homo sapiens 0-7 29636622-3 2018 The current study aimed to explore the potential function of miR-206 in 5-FU resistance. Fluorouracil 72-76 microRNA 206 Homo sapiens 61-68 29636622-5 2018 miR-206 mimic was transfected to 5-FU-FR CRC, and the 5-FU sensitivity was detected by MTS and flow cytometry. Fluorouracil 33-37 microRNA 206 Homo sapiens 0-7 29636622-9 2018 We also identified miR-206 targeting Bcl-2 directly in CRC, which is required for miR-206 mediated-5-FU resistance. Fluorouracil 99-103 microRNA 206 Homo sapiens 19-26 29636622-9 2018 We also identified miR-206 targeting Bcl-2 directly in CRC, which is required for miR-206 mediated-5-FU resistance. Fluorouracil 99-103 microRNA 206 Homo sapiens 82-89 28377359-5 2017 The effect of miR-206 on the sensitivity of ovarian cancer cells to 5-Fu was assessed. Fluorouracil 68-72 microRNA 206 Homo sapiens 14-21 28377359-10 2017 Transfection of SKOV3 cells with miR-206 significantly lowered the IC50 of 5-Fu to enhance the chemotherapy sensitivity of the cells to 5-Fu. Fluorouracil 75-79 microRNA 206 Homo sapiens 33-40 28377359-10 2017 Transfection of SKOV3 cells with miR-206 significantly lowered the IC50 of 5-Fu to enhance the chemotherapy sensitivity of the cells to 5-Fu. Fluorouracil 136-140 microRNA 206 Homo sapiens 33-40 28377359-11 2017 CONCLUSION: As a potential tumor suppressor, miR-206 directly targets CDK4 to suppress the cell growth and enhance the chemotherapy sensitivity to 5-Fu in ovarian cancer cells in vitro. Fluorouracil 147-151 microRNA 206 Homo sapiens 45-52