PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35103981-11	2022	5-FU suppressed the stemness maintenance of CSCs in PANC-1 cells, as demonstrated by the inhibition of tumorsphere formation, the decrease in CD44+CD133+ cells" fraction, and downregulation of OCT4, Nanog, and SOX2 expression.	Fluorouracil	0-4	Nanog homeobox	Homo sapiens	199-204	
22205615-5	2012	Also, mock-knockdown and NANOG-knockdown cells were treated with 5-fluorouracil (5-FU) and survival rate was measured by MTT assay to evaluate drug sensitivity.	Fluorouracil	65-79	Nanog homeobox	Homo sapiens	25-30	
22205615-5	2012	Also, mock-knockdown and NANOG-knockdown cells were treated with 5-fluorouracil (5-FU) and survival rate was measured by MTT assay to evaluate drug sensitivity.	Fluorouracil	81-85	Nanog homeobox	Homo sapiens	25-30	
22205615-7	2012	NANOG knockdown suppressed proliferation, colony formation, and in vivo tumorigenicity but increased the sensitivity to 5-FU of SW620 cells.	Fluorouracil	120-124	Nanog homeobox	Homo sapiens	0-5	
22205615-8	2012	5-FU treatment greatly inhibited the expression of the major stemness-associated genes NANOG, OCT4, and SOX2.	Fluorouracil	0-4	Nanog homeobox	Homo sapiens	87-92	
22993328-7	2012	RESULTS: The frequency of cells that were capable of initiating spheres was higher in 5-FU-pre treated cells, which also overexpressed stem cell marker genes, OCT4 and NANOG.	Fluorouracil	86-90	Nanog homeobox	Homo sapiens	168-173	
34168463-3	2021	The expressions of OCT3/4 and Nanog in cells treated with 5-Fu or CDDP were measured by immunofluorescence, Western blot and qPCR.	Fluorouracil	58-62	Nanog homeobox	Homo sapiens	30-35	
30451890-7	2018	Further, corresponding to CD44v6 knockdown cells, 5FU+ Silibinin treatment significantly decreased CD44v6, Nanog, CTNNB1 and CDKN2A expression whereas increased E-cadherin expression in HCT116 derived CD44+ cells.	Fluorouracil	50-53	Nanog homeobox	Homo sapiens	107-112	
33460610-0	2021	Suppression of Nanog inhibited cell migration and increased the sensitivity of colorectal cancer cells to 5-fluorouracil.	Fluorouracil	106-120	Nanog homeobox	Homo sapiens	15-20	
33460610-2	2021	Therefore, this study was aimed to evaluate the Nanog suppression effect using small interference RNA (siRNA) combined with 5-fluorouracil (5-FU) on CRC cells.	Fluorouracil	124-138	Nanog homeobox	Homo sapiens	48-53	
33460610-2	2021	Therefore, this study was aimed to evaluate the Nanog suppression effect using small interference RNA (siRNA) combined with 5-fluorouracil (5-FU) on CRC cells.	Fluorouracil	140-144	Nanog homeobox	Homo sapiens	48-53	
33460610-3	2021	Nanog-overexpressing SW-480 cells were transfected with Nanog si-RNA and treated with 5-FU, in combination or separately.	Fluorouracil	86-90	Nanog homeobox	Homo sapiens	0-5	
33460610-5	2021	Furthermore, Nanog knockdown significantly increased CRC cell sensitivity to 5-FU drug via modulating Bax and Bcl-2 mRNA expression.	Fluorouracil	77-81	Nanog homeobox	Homo sapiens	13-18