PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7056021-2 1982 The in vivo metabolism of antipyrine, which is also catalyzed by microsomal cytochrome P-450-dependent monooxygenases, has been reported to be correlated with AHH inducibility in human lymphocytes. Antipyrine 26-36 cytochrome P450 family 1 subfamily A member 2 Homo sapiens 159-162 14570767-8 2003 Mechanism-based inhibition of CYP1A2 may explain why zileuton decreases the oral clearance of antipyrine, propranolol, (R)-warfarin, and theophylline, at doses that have a minimal effect on the pharmacokinetics of (S)-warfarin, phenytoin, and terfenadine. Antipyrine 94-104 cytochrome P450 family 1 subfamily A member 2 Homo sapiens 30-36 11847531-9 2002 Since the CL(T) of antipyrine is a general measure of CYP enzymes but with a slight to moderate weight toward CYP1A2, we suggest the involvement of this enzyme in ASOX to ASON metabolism in man. Antipyrine 19-29 cytochrome P450 family 1 subfamily A member 2 Homo sapiens 110-116 11124226-9 2001 In addition, our results suggest CYP1A2 inhibition as the mechanism behind the observed thiabendazole/theophylline and primaquine/antipyrine interactions in vivo. Antipyrine 130-140 cytochrome P450 family 1 subfamily A member 2 Homo sapiens 33-39