PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 875465-0 1977 Physiologic mechanisms of bupicomide- and hydralazine-induced increase in plasma renin activity in hypertensive patients. bupicomide 26-36 renin Homo sapiens 81-86 875465-1 1977 A study was made of the possible mechanisms underlying bupicomide- and hydralazine-induced increase of plasma renin activity. bupicomide 55-65 renin Homo sapiens 110-115 875465-7 1977 Plasma renin activity during bupicomide and hydralazine administration correlated positively with control plasma renin activity (r = 0.98, P less than 0.001). bupicomide 29-39 renin Homo sapiens 7-12 875465-9 1977 We conclude that control plasma renin activity is a major determinant of change in plasma renin activity during administration of bupicomide or hydralazine. bupicomide 130-140 renin Homo sapiens 32-37 875465-9 1977 We conclude that control plasma renin activity is a major determinant of change in plasma renin activity during administration of bupicomide or hydralazine. bupicomide 130-140 renin Homo sapiens 90-95 875465-10 1977 Both an increase in sympathetic activity and a decrease in perfusion pressure may contribute to the bupicomide- and hydralazine-induced increase in plasma renin activity, possibly by a baroreceptor-mediated increase in adrenergic tone. bupicomide 100-110 renin Homo sapiens 155-160