PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 14758635-3 2003 Administration of prolactin prior to hydrocortisone administration induced alteration in the level of corticosterone that depended on the dose of hydrocortisone. Hydrocortisone 146-160 prolactin Rattus norvegicus 18-27 1970119-2 1990 PRL caused a dose-dependent (10-1000 ng/ml) decrease in P450arom mRNA and E biosynthesis (greater than 99%) in luteinized rat granulosa cells in vitro, even when the cells were cultured in the presence of insulin and hydrocortisone (hormones known to synergize with PRL to induce proteins in mammary tissue) or in the presence of forskolin (a nonhormonal stimulator of cAMP). Hydrocortisone 217-231 prolactin Rattus norvegicus 0-3 2890379-3 1987 However, the stimulatory effect of estradiol and the inhibitory effect of hydrocortisone on prolactin synthesis can be demonstrated in the prolactin-producing GH cell strain, GH4C1. Hydrocortisone 74-88 prolactin Rattus norvegicus 92-101 2906115-1 1988 Cortisol administered at a dose of 25 mg/kg 24 h before measurements decreased the prolactin secretion induced by intraventricularly given opioids (dynorphin, beta-endorphin, Met-enkephalin or D-Met-Pro-enkephalinamide). Hydrocortisone 0-8 prolactin Rattus norvegicus 83-92 2906115-5 1988 The present results show that the cortisol-induced inhibition of opioid-induced prolactin secretion is dependent on protein synthesis and independent of changes in drug metabolism, and of the type of opiate receptor preferentially affected by the opiate agonists employed. Hydrocortisone 34-42 prolactin Rattus norvegicus 80-89 2890379-3 1987 However, the stimulatory effect of estradiol and the inhibitory effect of hydrocortisone on prolactin synthesis can be demonstrated in the prolactin-producing GH cell strain, GH4C1. Hydrocortisone 74-88 prolactin Rattus norvegicus 139-148 3593199-2 1987 The induction of prolactin (PRL)-gene expression by calcitriol (1,25-dihydroxyvitamin D3, 1,25-dihydroxycholecalciferol) in clonal rat pituitary tumour (GH4C1) cells was selectively inhibited by cortisol [IC50 (concentration causing 50% inhibition) = 3.2-4.1 nM]. Hydrocortisone 195-203 prolactin Rattus norvegicus 17-26 3593199-2 1987 The induction of prolactin (PRL)-gene expression by calcitriol (1,25-dihydroxyvitamin D3, 1,25-dihydroxycholecalciferol) in clonal rat pituitary tumour (GH4C1) cells was selectively inhibited by cortisol [IC50 (concentration causing 50% inhibition) = 3.2-4.1 nM]. Hydrocortisone 195-203 prolactin Rattus norvegicus 28-31 3593199-3 1987 The steroid specificity of this effect was investigated and various steroids were found to inhibit calcitriol-stimulated PRL production with the following relative potencies: cortisol, 1; dexamethasone, 8; 11-deoxycortisol, 0.5; corticosterone, 0.4; aldosterone, 0.07; testosterone and oestradiol, less than 0.003. Hydrocortisone 175-183 prolactin Rattus norvegicus 121-124 2986721-5 1985 On the other hand, hydrocortisone treatment of sham-operated rats reduced prolactin binding by 57% and dexamethasone binding by 76%. Hydrocortisone 19-33 prolactin Rattus norvegicus 74-83 3082326-7 1986 Calcitriol-induced PRL mRNA fell by more than 50% at 25 h and reached the control level 50 h after treatment with cortisol. Hydrocortisone 114-122 prolactin Rattus norvegicus 19-22 3082326-8 1986 The inhibition by cortisol of calcitriol induction of PRL production was selective when compared with effects on other inducers of PRL-gene expression [thyroliberin, epidermal growth factor and phorbol myristate acetate ("12-omicron-tetradecanoylphorbol 13-acetate")]. Hydrocortisone 18-26 prolactin Rattus norvegicus 54-57 6716033-3 1984 The injection of a large dose of cortisol (25 mg/kg, s.c.) also evoked an inhibition of morphine-induced prolactin release. Hydrocortisone 33-41 prolactin Rattus norvegicus 105-114 6371058-7 1984 Insulin also reversed the suppression of prolactin (PRL) secretion induced by hydrocortisone (1 uM), and actually stimulated basal PRL secretion by over 50%. Hydrocortisone 78-92 prolactin Rattus norvegicus 41-50 3920651-4 1985 Administration of cortisol decreased the content of prolactin in intact, but not in malnourished rats. Hydrocortisone 18-26 prolactin Rattus norvegicus 52-61 3920651-6 1985 Cortisol treatment increased incorporation of tritiated amino acids into pituitary prolactin. Hydrocortisone 0-8 prolactin Rattus norvegicus 83-92 6315507-3 1983 In this system, prolactin showed a modest but significant growth-stimulatory activity (50% over control), and addition of insulin or hydrocortisone or both enhanced the growth stimulation of prolactin to a large extent. Hydrocortisone 133-147 prolactin Rattus norvegicus 191-200 436735-4 1979 Either cortisol or lithium could completely block the PRL effect. Hydrocortisone 7-15 prolactin Rattus norvegicus 54-57 5513559-9 1970 Hydrocortisone (3 x 10(-6)M), which stimulated the production of growth hormone 4- to 8-fold in most of the cell strains, reduced the rate of prolactin production to less than 25% of that in control cultures. Hydrocortisone 0-14 prolactin Rattus norvegicus 142-151 816463-4 1976 Daily injection of ovine prolactin and hydrocortisone suppressed endogenous prolactin release but significantly increased tumore size and number. Hydrocortisone 39-53 prolactin Rattus norvegicus 76-85 632273-6 1978 Further data indicate that two steroid hormones, hydrocortisone and progesterone, were able to modulate the prolactin-induced accumulation of casein mRNA. Hydrocortisone 49-63 prolactin Rattus norvegicus 108-117 632273-10 1978 Thus, hydrocortisone appears to potentiate the prolactin induction of casein mRNA, whereas progesterone is able to prevent casein mRNA accumulation. Hydrocortisone 6-20 prolactin Rattus norvegicus 47-56 4199262-0 1973 Effects of thyrotropin-releasing hormone and hydrocortisone on synthesis and degradation of prolactin in a rat pituitary cell strain. Hydrocortisone 45-59 prolactin Rattus norvegicus 92-101