PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32061436-5	2020	Mechanistically cadmium-mediated OCT2 translocation was found to involve protein-protein interaction between serine/threonine-protein kinase AKT2, calcium/calmodulin and the AKT substrate AS160 in in vitro cellular studies.	cholecystokinin C-terminal flanking peptide	109-115	AKT serine/threonine kinase 1	Homo sapiens	141-144	
31863285-4	2020	In certain cell types, IL-18 also activates mitogen-activated protein kinases (MAPKs) and phosphoinositide 3-kinase/ AKT serine/threonine kinase (PI3K/AKT) signaling modules leading to the production and release of proinflammatory cytokines.	cholecystokinin C-terminal flanking peptide	121-127	AKT serine/threonine kinase 1	Homo sapiens	117-120	
32005903-1	2020	p21-activated kinases (PAKs) are protein serine/threonine kinases stimulated by Rho-family p21 GTPases such as CDC42 and RAC.	cholecystokinin C-terminal flanking peptide	41-47	AKT serine/threonine kinase 1	Homo sapiens	121-124	
32067263-2	2021	Akt regulates a wide variety of cell processes including cell proliferation, survival, and angiogenesis through serine/threonine phosphorylation of downstream targets including mTOR and glycogen-synthase-kinase-3-beta (GSK3beta).	cholecystokinin C-terminal flanking peptide	112-118	AKT serine/threonine kinase 1	Homo sapiens	0-3	
31962201-1	2020	The serine/arginine protein kinases respond to the EGFR-PI3K-AKT signaling module in the context of pre-mRNA alternative splicing regulation.	cholecystokinin C-terminal flanking peptide	4-10	AKT serine/threonine kinase 1	Homo sapiens	61-64	
31952070-4	2020	AKT and mTOR are serine/threonine kinases which play important roles in cell growth, proliferation, survival, and differentiation.	cholecystokinin C-terminal flanking peptide	17-23	AKT serine/threonine kinase 1	Homo sapiens	0-3	
32075106-1	2020	The serine/threonine protein kinase AKT1 is a downstream target of the chemokine receptor 4 (CXCR4), and both proteins play a central role in the modulation of diverse cellular processes, including proliferation and cell survival.	cholecystokinin C-terminal flanking peptide	4-10	AKT serine/threonine kinase 1	Homo sapiens	36-40	
32054790-5	2020	XENT or XENT+ENZA inhibited IGF type 1 receptor (IGF-1R) and AKT serine/threonine kinase (AKT) phosphorylation in VCaP, DuCaP, and MDA PCa 2b cells; XENT had no effect on AKT phosphorylation and proliferation in PTEN-null LNCaP or PC-3 cells.	cholecystokinin C-terminal flanking peptide	65-71	AKT serine/threonine kinase 1	Homo sapiens	61-64	
32054790-5	2020	XENT or XENT+ENZA inhibited IGF type 1 receptor (IGF-1R) and AKT serine/threonine kinase (AKT) phosphorylation in VCaP, DuCaP, and MDA PCa 2b cells; XENT had no effect on AKT phosphorylation and proliferation in PTEN-null LNCaP or PC-3 cells.	cholecystokinin C-terminal flanking peptide	65-71	AKT serine/threonine kinase 1	Homo sapiens	90-93	
32054790-5	2020	XENT or XENT+ENZA inhibited IGF type 1 receptor (IGF-1R) and AKT serine/threonine kinase (AKT) phosphorylation in VCaP, DuCaP, and MDA PCa 2b cells; XENT had no effect on AKT phosphorylation and proliferation in PTEN-null LNCaP or PC-3 cells.	cholecystokinin C-terminal flanking peptide	65-71	AKT serine/threonine kinase 1	Homo sapiens	90-93	
31932471-4	2020	Mechanistically, we find that SMAD4 interacts with and inhibits RICTOR, a component of the mTORC2 complex, resulting in suppression of downstream effector phosphorylation of AKT at Serine 473.	cholecystokinin C-terminal flanking peptide	181-187	AKT serine/threonine kinase 1	Homo sapiens	174-177	
32035020-1	2020	BACKGROUND: Capivasertib (AZD5363) is a potent selective oral inhibitor of all three isoforms of the serine/threonine kinase AKT.	cholecystokinin C-terminal flanking peptide	101-107	AKT serine/threonine kinase 1	Homo sapiens	125-128	
31612389-10	2019	Moreover, CPA6 could activate AKT serine/threonine kinase (AKT) signaling pathway as confirmed by Western blotting.	cholecystokinin C-terminal flanking peptide	34-40	AKT serine/threonine kinase 1	Homo sapiens	30-33	
31612389-10	2019	Moreover, CPA6 could activate AKT serine/threonine kinase (AKT) signaling pathway as confirmed by Western blotting.	cholecystokinin C-terminal flanking peptide	34-40	AKT serine/threonine kinase 1	Homo sapiens	59-62	
31897207-5	2020	The present study used the phosphorylation of Akt1 protein at serine 473 (pAkt473) as an indicator of signaling activation.	cholecystokinin C-terminal flanking peptide	62-68	AKT serine/threonine kinase 1	Homo sapiens	46-50	
31548394-1	2019	The Pim and AKT serine/threonine protein kinases are implicated as drivers of cancer.	cholecystokinin C-terminal flanking peptide	16-22	AKT serine/threonine kinase 1	Homo sapiens	12-15