PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31570196-3 2019 Recently, the accumulation of p16INK4a-positive cells in the kidney has been considered a molecular feature of renal senescence, with the p16INK4a gene reportedly regulated by mixed-lineage leukemia 1 (MLL1)/WD-40 repeat protein 5 (WDR5)-mediated histone 3 lysine 4 trimethylation (H3K4me3). tyrosyl-lysine 257-263 cyclin dependent kinase inhibitor 2A Mus musculus 138-146