PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32001024-3 2020 Novel factors have been identified that ensure DSB-induced silencing via two distinct pathways: direct inhibition of RNA Polymerase II (Pol II) mediated by negative elongation factor (NELF), and histone code editing by CDYL1 and histone deacetylases (HDACs) that catalyze H3K27me3 and erase lysine crotonylation, respectively. tyrosyl-lysine 291-297 chromodomain Y like Homo sapiens 219-224