PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 14975696-5 2004 In a dose-dependent manner, ibudilast suppressed the production of nitric oxide (NO), reactive oxygen species, interleukin (IL)-1beta, IL-6, and tumor necrosis factor (TNF)-alpha and enhanced the production of the inhibitory cytokine, IL-10, and additional neurotrophic factors, including nerve growth factor (NGF), glia-derived neurotrophic factor (GDNF), and neurotrophin (NT)-4 in activated microglia. ibudilast 28-37 interleukin 1 beta Homo sapiens 111-133