PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23711784-2 2013 Carboxyl functionalized MSN (MSN/COOH) was firstly prepared and then modified with folate as the cancer targeting moiety and a near infrared fluorescent dye as labeling segment. Carbonic Acid 33-37 moesin Homo sapiens 24-27 24940057-2 2014 MSN@Alg microspheres have the advantages of MSN and alginate, where MSN provides a large surface area for high drug loading and alginate provides excellent biocompatibility and COOH functionality for specific targeting. Carbonic Acid 177-181 moesin Homo sapiens 0-3 23711784-3 2013 Folate was conjugated to MSN/COOH via functional polyethyleneglycol (PEG), constructing the vector MSN/COOH-PEG-FA. Carbonic Acid 29-33 moesin Homo sapiens 99-102 23711784-3 2013 Folate was conjugated to MSN/COOH via functional polyethyleneglycol (PEG), constructing the vector MSN/COOH-PEG-FA. Carbonic Acid 103-107 moesin Homo sapiens 25-28 23711784-3 2013 Folate was conjugated to MSN/COOH via functional polyethyleneglycol (PEG), constructing the vector MSN/COOH-PEG-FA. Carbonic Acid 103-107 moesin Homo sapiens 99-102 30203954-3 2018 A zeolitic imidazole framework-8 (ZIF-8) film with a few nanometer thickness was in situ synthesized on the surface of carboxylated mesoporous silica (MSN-COOH) nanoparticles (NPs) for pore blocking and efficient loading of small interfering RNAs to fabricate a pH-responsive drug delivery system. Carbonic Acid 155-159 moesin Homo sapiens 151-154 30486276-2 2018 We firstly synthesized carboxyl-modified mesoporous silica nanoparticles (MSN-COOH) via two-step synthesis, and then developed calcium leucovorin (LV)-loaded carboxyl-modified mesoporous silica nanoparticles based on galactosylated chitosan (GC), which are galectin receptor-mediated materials for colon-specific drug delivery systems. Carbonic Acid 78-82 moesin Homo sapiens 74-77 30486276-5 2018 LV@MSN-COOH/GC had a high LV loading and a drug loading of 18.07%. Carbonic Acid 7-11 moesin Homo sapiens 3-6 30486276-7 2018 Cell experiments showed that in SW620 cells with the galectin receptor, the LV@MSN-COOH/GC metabolized into methyl tetrahydrofolic acid (MTHF) and 5-fluorouracil (5-FU)@MSN-NH2/GC metabolized into FdUMP in vivo. Carbonic Acid 83-87 moesin Homo sapiens 79-82 30486276-7 2018 Cell experiments showed that in SW620 cells with the galectin receptor, the LV@MSN-COOH/GC metabolized into methyl tetrahydrofolic acid (MTHF) and 5-fluorouracil (5-FU)@MSN-NH2/GC metabolized into FdUMP in vivo. Carbonic Acid 83-87 moesin Homo sapiens 169-172 30347763-6 2018 Specifically, MSN-COOH exhibited the highest loading capacity. Carbonic Acid 18-22 moesin Homo sapiens 14-17 30347763-9 2018 Altogether, these results demonstrate that MSN-COOH could be a promising system to achieve a controlled release of PTM. Carbonic Acid 47-51 moesin Homo sapiens 43-46 17428844-4 2007 Cell swelling increased the interaction between actin and moesin and induced the transition of moesin from an oligomeric to a monomeric functional conformation, characterized by both the COOH- and NH(2)-terminal domains being exposed. Carbonic Acid 187-191 moesin Homo sapiens 95-101 33830730-2 2021 In our work, we fabricated mesoporous silica nanoparticles with modification groups (MSN-NH2@COOH/CPP5) that effectively penetrated the mucus layer and passed through the intestinal epithelium by mimicking the virus surface. Carbonic Acid 93-97 moesin Homo sapiens 85-88 33830730-6 2021 The KLPVM peptide enhanced the uptake of MSN-NH2@COOH/CPP5 by coculturing Caco-2 and E12 cells as an intestinal epithelium model. Carbonic Acid 49-53 moesin Homo sapiens 41-44 33830730-8 2021 Indeed, for MSN-NH2@COOH/CPP5, the transepithelial transport of the Caco-2 cell monolayer was 2.4-fold higher than MSN@NH2 and 2.0-fold higher than MSN-NH2@COOH. Carbonic Acid 20-24 moesin Homo sapiens 12-15 33830730-8 2021 Indeed, for MSN-NH2@COOH/CPP5, the transepithelial transport of the Caco-2 cell monolayer was 2.4-fold higher than MSN@NH2 and 2.0-fold higher than MSN-NH2@COOH. Carbonic Acid 20-24 moesin Homo sapiens 115-118 33830730-8 2021 Indeed, for MSN-NH2@COOH/CPP5, the transepithelial transport of the Caco-2 cell monolayer was 2.4-fold higher than MSN@NH2 and 2.0-fold higher than MSN-NH2@COOH. Carbonic Acid 20-24 moesin Homo sapiens 115-118 33830730-8 2021 Indeed, for MSN-NH2@COOH/CPP5, the transepithelial transport of the Caco-2 cell monolayer was 2.4-fold higher than MSN@NH2 and 2.0-fold higher than MSN-NH2@COOH. Carbonic Acid 156-160 moesin Homo sapiens 12-15 33830730-8 2021 Indeed, for MSN-NH2@COOH/CPP5, the transepithelial transport of the Caco-2 cell monolayer was 2.4-fold higher than MSN@NH2 and 2.0-fold higher than MSN-NH2@COOH. Carbonic Acid 156-160 moesin Homo sapiens 115-118 33830730-8 2021 Indeed, for MSN-NH2@COOH/CPP5, the transepithelial transport of the Caco-2 cell monolayer was 2.4-fold higher than MSN@NH2 and 2.0-fold higher than MSN-NH2@COOH. Carbonic Acid 156-160 moesin Homo sapiens 115-118 30203954-4 2018 The ZIF-8 film could convert the charge of MSN-COOH from negative to positive for efficient loading of siRNA via electrostatic interactions and protect siRNA from nuclease degradation. Carbonic Acid 47-51 moesin Homo sapiens 43-46 27346782-1 2016 In this paper, a biocompatible and water-soluble fluorescent fullerene (C60-TEG-COOH) coated mesoporous silica nanoparticle (MSN) was successfully fabricated for pH-sensitive drug release and fluorescent cell imaging. Carbonic Acid 80-84 moesin Homo sapiens 125-128