PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23412107-3 2013 METHODS: We developed a phosphoshift (pShift) flow cytometry-based test that measures RAF signal transduction capacity in peripheral blood cells, and evaluated it in a phase II clinical trial of oral sorafenib plus low-dose cyclophosphamide in patients with advanced neuroendocrine tumours (NETs), in order to predict clinical course and/or guide individual dose-titration. Cyclophosphamide 224-240 zinc fingers and homeoboxes 2 Homo sapiens 86-89 23412107-8 2013 CONCLUSION: The pharmacodynamic assessment of RAF transduction may identify selected patients with advanced NETs most likely to benefit from the combination of sorafenib plus cyclophosphamide. Cyclophosphamide 175-191 zinc fingers and homeoboxes 2 Homo sapiens 46-49