PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25677905-1 2015 The most important cytotoxic drug namely, cyclophosphamide used in breast cancer along with epirubicin and 5-fluorouracil, is transported by ABCC transporters and detoxified by glutathione S-transferases (GSTs). Cyclophosphamide 42-58 ATP binding cassette subfamily C member 1 Homo sapiens 141-145 32010961-5 2020 This association is highly drug-specific for subgroups treated with the MRP1 substrates cyclophosphamide (log-rank p = 0.0011) and doxorubicin (log-rank p = 0.0088) independent of age and tumor stage, whereas no association was found in individuals treated with tamoxifen (log-rank p = 0.13). Cyclophosphamide 88-104 ATP binding cassette subfamily C member 1 Homo sapiens 72-76 23396606-0 2013 Genetic variability in the multidrug resistance associated protein-1 (ABCC1/MRP1) predicts hematological toxicity in breast cancer patients receiving (neo-)adjuvant chemotherapy with 5-fluorouracil, epirubicin and cyclophosphamide (FEC). Cyclophosphamide 214-230 ATP binding cassette subfamily C member 1 Homo sapiens 27-68 23396606-0 2013 Genetic variability in the multidrug resistance associated protein-1 (ABCC1/MRP1) predicts hematological toxicity in breast cancer patients receiving (neo-)adjuvant chemotherapy with 5-fluorouracil, epirubicin and cyclophosphamide (FEC). Cyclophosphamide 214-230 ATP binding cassette subfamily C member 1 Homo sapiens 70-75 23396606-0 2013 Genetic variability in the multidrug resistance associated protein-1 (ABCC1/MRP1) predicts hematological toxicity in breast cancer patients receiving (neo-)adjuvant chemotherapy with 5-fluorouracil, epirubicin and cyclophosphamide (FEC). Cyclophosphamide 214-230 ATP binding cassette subfamily C member 1 Homo sapiens 76-80 12894554-5 2003 The response of xenografted ALL toward vincristine and cyclophosphamide was inversely correlated with the expression of P-gp, LRP and MRP1 (R2 = 0.71, 0.70 and 0.64 for vincristine and 0.44, 0.70 and 0.60 for cyclophosphamide). Cyclophosphamide 55-71 ATP binding cassette subfamily C member 1 Homo sapiens 134-138 12894554-5 2003 The response of xenografted ALL toward vincristine and cyclophosphamide was inversely correlated with the expression of P-gp, LRP and MRP1 (R2 = 0.71, 0.70 and 0.64 for vincristine and 0.44, 0.70 and 0.60 for cyclophosphamide). Cyclophosphamide 209-225 ATP binding cassette subfamily C member 1 Homo sapiens 134-138 12576456-8 2003 However, in the subgroup of patients treated with anthracycline-based chemotherapy (5-fluorouracil, Adriamycin/epirubicin, and cyclophosphamide), a correlation between response and the expression of BCRP and MRP1 (only PFS) was found, whereas such an association was not present in the cyclophosphamide, methotrexate, and 5-fluorouracil-treated group of patients. Cyclophosphamide 127-143 ATP binding cassette subfamily C member 1 Homo sapiens 208-212