PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8940232-0 1996 Lipoteichoic acid from viridans streptococci induces the production of tumor necrosis factor and nitric oxide by murine macrophages. lipoteichoic acid 0-17 tumor necrosis factor Mus musculus 71-92 12675685-5 2003 When media conditioned by Lactobacillus rhamnosus GG (LGG) are co-incubated with lipopolysaccharide (LPS) or lipoteichoic acid (LTA), TNF-alpha production is significantly inhibited compared to controls, whereas IL-10 synthesis is unaffected. lipoteichoic acid 109-126 tumor necrosis factor Mus musculus 134-143 11165269-2 2001 In this study, we show that ES products suppressed tumor necrosis factor-alpha mRNA expression and tumor necrosis factor-alpha production in murine peritoneal macrophages stimulated with lipopolysaccharide or lipoteichoic acid in vitro. lipoteichoic acid 209-226 tumor necrosis factor Mus musculus 51-78 10569765-6 1999 Exposure of macrophages to a mixture of HlpA and lipoteichoic acid resulted in a synergistic response in the production of both TNF-alpha and IL-1. lipoteichoic acid 49-66 tumor necrosis factor Mus musculus 128-137 8940232-2 1996 Lipoteichoic acid (LTA) purified from 2 strains of viridans streptococci induced the accumulation of tumor necrosis factor (TNF) mRNA and protein by the murine macrophage cell line RAW 264.7 in a dose- and time-dependent manner. lipoteichoic acid 0-17 tumor necrosis factor Mus musculus 101-122 8940232-2 1996 Lipoteichoic acid (LTA) purified from 2 strains of viridans streptococci induced the accumulation of tumor necrosis factor (TNF) mRNA and protein by the murine macrophage cell line RAW 264.7 in a dose- and time-dependent manner. lipoteichoic acid 0-17 tumor necrosis factor Mus musculus 124-127 8940232-2 1996 Lipoteichoic acid (LTA) purified from 2 strains of viridans streptococci induced the accumulation of tumor necrosis factor (TNF) mRNA and protein by the murine macrophage cell line RAW 264.7 in a dose- and time-dependent manner. lipoteichoic acid 19-22 tumor necrosis factor Mus musculus 101-122 8940232-2 1996 Lipoteichoic acid (LTA) purified from 2 strains of viridans streptococci induced the accumulation of tumor necrosis factor (TNF) mRNA and protein by the murine macrophage cell line RAW 264.7 in a dose- and time-dependent manner. lipoteichoic acid 19-22 tumor necrosis factor Mus musculus 124-127 8731214-0 1996 Synergistic induction of tumor necrosis factor alpha by bacterial lipopolysaccharide and lipoteichoic acid in combination with polytetrafluoroethylene particles in a murine macrophage cell line RAW 264.7. lipoteichoic acid 89-106 tumor necrosis factor Mus musculus 25-52 33313945-5 2021 Following shikonin treatment, the accumulation of pulmonary neutrophils and expression of TNFalpha, IL-1beta and IL-6 were decreased in mice with LTA-induced ALI. lipoteichoic acid 146-149 tumor necrosis factor Mus musculus 90-98 33303231-0 2021 HEMA-induced oxidative stress inhibits NF-kappaB nuclear translocation and TNF release from LTA- and LPS-stimulated immunocompetent cells. lipoteichoic acid 92-95 tumor necrosis factor Mus musculus 75-78 33303231-3 2021 The present investigation presents evidence regarding the role of HEMA-induced oxidative stress in the secretion of the pro-inflammatory cytokine TNFalpha from cells exposed to the antigens LTA (lipoteichoic acid) or LPS (lipopolysaccharide) of cariogenic microorganisms using BSO (L-buthionine sulfoximine) or NAC (N-acetyl cysteine) to inhibit or stabilize the amounts of the antioxidant glutathione. lipoteichoic acid 190-193 tumor necrosis factor Mus musculus 146-154 33303231-3 2021 The present investigation presents evidence regarding the role of HEMA-induced oxidative stress in the secretion of the pro-inflammatory cytokine TNFalpha from cells exposed to the antigens LTA (lipoteichoic acid) or LPS (lipopolysaccharide) of cariogenic microorganisms using BSO (L-buthionine sulfoximine) or NAC (N-acetyl cysteine) to inhibit or stabilize the amounts of the antioxidant glutathione. lipoteichoic acid 195-212 tumor necrosis factor Mus musculus 146-154 33303231-7 2021 RESULTS: The release of TNFalpha in both LTA- and LPS-exposed cells was decreased by HEMA, and this concentration-dependent inhibitory effect was amplified by BSO or NAC. lipoteichoic acid 41-44 tumor necrosis factor Mus musculus 24-32 33303231-9 2021 CONCLUSIONS: A disturbance of the cellular redox balance, particularly induced by HEMA, is a crucial factor in the inhibition of LTA- and LPS-stimulated signalling pathways leading to TNFalpha secretion. lipoteichoic acid 129-132 tumor necrosis factor Mus musculus 184-192 27231239-4 2016 In the current study, we found that lipoteichoic acid isolated from Lactobacillus plantarum K8 (pLTA) inhibited tumor necrosis factor-alpha (TNF-alpha) or interferon-gamma (IFN-gamma)-mediated C3 mRNA and protein expression in HaCaT cells. lipoteichoic acid 36-53 tumor necrosis factor Mus musculus 141-150 28702588-2 2017 The most selective compound bore promising activity against biofilm-related infections and intracellular bacteria, and also suppressed the stimulation of TNF-alpha induced by lipoteichoic acid. lipoteichoic acid 175-192 tumor necrosis factor Mus musculus 154-163 27012236-2 2016 Lipoteichoic acid (LTA), a cell wall component of gram-positive bacteria, is known to induce the production of several cytokines such as TNF-alpha, IL-1beta, and IL-8 and affect the intestinal microflora, anti-aging, sepsis, and cholesterol level. lipoteichoic acid 0-17 tumor necrosis factor Mus musculus 137-146 27012236-2 2016 Lipoteichoic acid (LTA), a cell wall component of gram-positive bacteria, is known to induce the production of several cytokines such as TNF-alpha, IL-1beta, and IL-8 and affect the intestinal microflora, anti-aging, sepsis, and cholesterol level. lipoteichoic acid 19-22 tumor necrosis factor Mus musculus 137-146 19735715-9 2009 RESULTS: Lipoteichoic acid could significantly improve general appearance of the aging model mice, improve anti-oxidation activity in brain, increase IL-2 level and decrease TNF-alpha level in vitro and in vivo, respectively. lipoteichoic acid 9-26 tumor necrosis factor Mus musculus 174-183 25660311-0 2015 HMGB1 Binds to Lipoteichoic Acid and Enhances TNF-alpha and IL-6 Production through HMGB1-Mediated Transfer of Lipoteichoic Acid to CD14 and TLR2. lipoteichoic acid 111-128 tumor necrosis factor Mus musculus 46-55 25112321-3 2014 L. sakei and its lipoteichoic acid (LTA) have greater immune stimulating potential in IL-12, IFN-gamma, and TNF-alpha production as compared with L. plantarum in an in vitro condition. lipoteichoic acid 17-34 tumor necrosis factor Mus musculus 108-117 25112321-3 2014 L. sakei and its lipoteichoic acid (LTA) have greater immune stimulating potential in IL-12, IFN-gamma, and TNF-alpha production as compared with L. plantarum in an in vitro condition. lipoteichoic acid 36-39 tumor necrosis factor Mus musculus 108-117 23677476-3 2013 Secretion of the cytokines TNF-alpha and IL-6 by cultured macrophages (RAW264.7 cell line) was inhibited by these peptides in response to TLR2 activation by lipoteichoic acid (TLR2/6 activator) or palmitoyl (3)-Cys-Ser-Lys(4)-OH (TLR2/1 activator) but not by LPS (TLR4 activator). lipoteichoic acid 157-174 tumor necrosis factor Mus musculus 27-36 18387518-4 2008 Dendritic cells exposed to lipopolysaccharide, lipoteichoic acid and IL-1beta exhibited increase in the production of IL-12 p70 and TNF-alpha, increase in the formation of reactive oxygen species and nitric oxide, and elevation of intracellular Ca2+ levels. lipoteichoic acid 47-64 tumor necrosis factor Mus musculus 132-141 18845389-0 2009 A food-born heterocyclic amine, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), suppresses tumor necrosis factor-alpha expression in lipoteichoic acid-stimulated RAW 264.7 cells. lipoteichoic acid 141-158 tumor necrosis factor Mus musculus 99-126 18845389-3 2009 Here, we investigated the effect of PhIP on tumor necrosis factor-alpha (TNF-alpha) expression by murine macrophage-like cells (RAW 264.7) stimulated with lipoteichoic acid (LTA), a major virulence factor of Gram-positive bacteria. lipoteichoic acid 155-172 tumor necrosis factor Mus musculus 44-71 18845389-3 2009 Here, we investigated the effect of PhIP on tumor necrosis factor-alpha (TNF-alpha) expression by murine macrophage-like cells (RAW 264.7) stimulated with lipoteichoic acid (LTA), a major virulence factor of Gram-positive bacteria. lipoteichoic acid 155-172 tumor necrosis factor Mus musculus 73-82 18250466-0 2008 Lipoteichoic acid isolated from Lactobacillus plantarum inhibits lipopolysaccharide-induced TNF-alpha production in THP-1 cells and endotoxin shock in mice. lipoteichoic acid 0-17 tumor necrosis factor Mus musculus 92-101 16628628-9 2006 Injection of lipoteichoic acid, peptidoglycan (PGN), lipopolysaccharide (LPS), loxoribine, and oligonudeotide containing CpG (ISS-ODN) increased TNF-alpha mRNA expression more in the livers of EtOH-fed mice than in control mice. lipoteichoic acid 13-30 tumor necrosis factor Mus musculus 145-154 16899235-1 2006 BACKGROUND: Lipoteichoic acid (LTA) and lipopolysaccharide (LPS), the toxicants from bacteria, are potent inducers of inflammatory cytokines, such as tumor necrosis factor-alpha (TNF) and interleukin-1beta (IL-1). lipoteichoic acid 12-29 tumor necrosis factor Mus musculus 150-177 16899235-1 2006 BACKGROUND: Lipoteichoic acid (LTA) and lipopolysaccharide (LPS), the toxicants from bacteria, are potent inducers of inflammatory cytokines, such as tumor necrosis factor-alpha (TNF) and interleukin-1beta (IL-1). lipoteichoic acid 12-29 tumor necrosis factor Mus musculus 179-182 16899235-1 2006 BACKGROUND: Lipoteichoic acid (LTA) and lipopolysaccharide (LPS), the toxicants from bacteria, are potent inducers of inflammatory cytokines, such as tumor necrosis factor-alpha (TNF) and interleukin-1beta (IL-1). lipoteichoic acid 31-34 tumor necrosis factor Mus musculus 150-177 16899235-1 2006 BACKGROUND: Lipoteichoic acid (LTA) and lipopolysaccharide (LPS), the toxicants from bacteria, are potent inducers of inflammatory cytokines, such as tumor necrosis factor-alpha (TNF) and interleukin-1beta (IL-1). lipoteichoic acid 31-34 tumor necrosis factor Mus musculus 179-182 16912656-2 2006 Preliminary in vitro studies showed that both peptides, alone or combined, were able to inhibit the lipoteichoic acid-induced production of tumor necrosis factor alpha and nitric oxide by RAW 264.7 cells. lipoteichoic acid 100-117 tumor necrosis factor Mus musculus 140-167 15707667-3 2005 These peptides suppressed the induction of tumor necrosis factor alpha gene expression by lipopolysaccharide or lipoteichoic acid in murine macrophages, contributing to protection of mice from lethal MRSA infections in vivo. lipoteichoic acid 112-129 tumor necrosis factor Mus musculus 43-70 15003352-5 2004 In addition, these peptides suppressed tumor necrosis factor alpha (TNF-alpha) gene expression and production induced by lipopolysaccharide (LPS) or lipoteichoic acid (LTA) in murine macrophages. lipoteichoic acid 149-166 tumor necrosis factor Mus musculus 39-66 15003352-5 2004 In addition, these peptides suppressed tumor necrosis factor alpha (TNF-alpha) gene expression and production induced by lipopolysaccharide (LPS) or lipoteichoic acid (LTA) in murine macrophages. lipoteichoic acid 149-166 tumor necrosis factor Mus musculus 68-77 15003352-5 2004 In addition, these peptides suppressed tumor necrosis factor alpha (TNF-alpha) gene expression and production induced by lipopolysaccharide (LPS) or lipoteichoic acid (LTA) in murine macrophages. lipoteichoic acid 168-171 tumor necrosis factor Mus musculus 39-66 15003352-5 2004 In addition, these peptides suppressed tumor necrosis factor alpha (TNF-alpha) gene expression and production induced by lipopolysaccharide (LPS) or lipoteichoic acid (LTA) in murine macrophages. lipoteichoic acid 168-171 tumor necrosis factor Mus musculus 68-77 16206076-2 2005 METHODS: In in vitro experiments, the ability of temporin A to inhibit lipoteichoic acid-induced production of tumor necrosis factor (TNF)- alpha and nitric oxide (NO) was determined. lipoteichoic acid 71-88 tumor necrosis factor Mus musculus 111-145