PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 1649745-9 1991 The effect of OCT on osteocalcin secretion and alkaline phosphatase (ALP) activity in ROS 17/2.8 cells was also determined. maxacalcitol 14-17 bone gamma-carboxyglutamate protein Rattus norvegicus 21-32 1649745-10 1991 Pretreatment for 24 h with either 1,25-(OH)2D3 or OCT resulted in a dose-dependent enhancement of osteocalcin secretion. maxacalcitol 50-53 bone gamma-carboxyglutamate protein Rattus norvegicus 98-109 1649745-14 1991 Thus, OCT, like 1,25-(OH)2D3, up-regulates the vitamin D receptor, stimulates osteocalcin secretion, and increases ALP activity in ROS 17/2.8 cells, suggesting that the analog may be as active as 1,25-(OH)2D3 in stimulating bone formation in vivo. maxacalcitol 6-9 bone gamma-carboxyglutamate protein Rattus norvegicus 78-89