PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23588207-5	2013	We found that in RKO (human adenocarcinoma cell line) cells, MAT2A siRNA treatment lowered cellular SAMe and putrescine levels by 70-75%, increased apoptosis and inhibited growth.	Putrescine	109-119	methionine adenosyltransferase 2A	Homo sapiens	61-66	
23588207-6	2013	Putrescine supplementation blunted significantly MAT2A siRNA-induced apoptosis and growth suppression.	Putrescine	0-10	methionine adenosyltransferase 2A	Homo sapiens	49-54	
23588207-7	2013	Putrescine treatment (100pmol/L) raised MAT2A mRNA level to 4.3-fold of control, increased the expression of c-Jun and c-Fos and binding to an AP-1 site in the human MAT2A promoter and the promoter activity.	Putrescine	0-10	methionine adenosyltransferase 2A	Homo sapiens	40-45	
23588207-7	2013	Putrescine treatment (100pmol/L) raised MAT2A mRNA level to 4.3-fold of control, increased the expression of c-Jun and c-Fos and binding to an AP-1 site in the human MAT2A promoter and the promoter activity.	Putrescine	0-10	methionine adenosyltransferase 2A	Homo sapiens	166-171	
23588207-12	2013	Increased MAT2A expression provides more SAMe for polyamines biosynthesis; increased polyamine (putrescine in this case) can activate MAT2A at the transcriptional level.	Putrescine	96-106	methionine adenosyltransferase 2A	Homo sapiens	134-139