PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17327229-8 2007 Promoter-reporter assays showed that activity of the FAK promoter was increased in the N-MYC-amplified IMR-32 cell line, in the N-MYC-transfected SK-N-AS nonamplified cell line, and in the isogenic N-MYC(+) (Tet(-)) neuroblastoma cell lines compared with the nonamplified and N-MYC-nonexpressing cell lines. sk-n 146-150 MYCN proto-oncogene, bHLH transcription factor Homo sapiens 128-133 21384249-7 2011 The MYCN-amplified cell line (IMR32) aggregated much more rapidly than the unamplified cell lines, as indicated by a significantly lower area under its aggregation curve (single non-aggregated cells vs. time): IMR32=4.3, CHP-212 =12.4, SK-N-AS=9.8 (adhesion index x10(5)). sk-n 236-240 MYCN proto-oncogene, bHLH transcription factor Homo sapiens 4-8 17327229-8 2007 Promoter-reporter assays showed that activity of the FAK promoter was increased in the N-MYC-amplified IMR-32 cell line, in the N-MYC-transfected SK-N-AS nonamplified cell line, and in the isogenic N-MYC(+) (Tet(-)) neuroblastoma cell lines compared with the nonamplified and N-MYC-nonexpressing cell lines. sk-n 146-150 MYCN proto-oncogene, bHLH transcription factor Homo sapiens 128-133 17327229-8 2007 Promoter-reporter assays showed that activity of the FAK promoter was increased in the N-MYC-amplified IMR-32 cell line, in the N-MYC-transfected SK-N-AS nonamplified cell line, and in the isogenic N-MYC(+) (Tet(-)) neuroblastoma cell lines compared with the nonamplified and N-MYC-nonexpressing cell lines. sk-n 146-150 MYCN proto-oncogene, bHLH transcription factor Homo sapiens 128-133 15258910-10 2004 Furthermore, when Mad1 or Mnt was overexpressed in SK-N-BE(2) cells they retained the capacity to differentiate, underscoring the notion that MYCN downregulation, and not changes in Mad/Mnt expression, is essential for neuroblastoma cell differentiation. sk-n 51-55 MYCN proto-oncogene, bHLH transcription factor Homo sapiens 142-146