PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19259017-3 2008 A functional polymorphism (COMT Val158Met) resulting in increased enzyme activity has been associated with polysubstance abuse and addiction to heroin and methamphetamine. Methamphetamine 155-170 catechol-O-methyltransferase Homo sapiens 27-31 19462300-8 2009 COMT, D4 receptor, and BDNF polymorphisms are linked to methamphetamine abuse and psychosis. Methamphetamine 56-71 catechol-O-methyltransferase Homo sapiens 0-4 15274053-0 2004 Association analysis of the DRD4 and COMT genes in methamphetamine abuse. Methamphetamine 51-66 catechol-O-methyltransferase Homo sapiens 37-41 17187009-0 2006 The COMT Val158Met polymorphism is associated with novelty seeking in Czech methamphetamine abusers: preliminary results. Methamphetamine 76-91 catechol-O-methyltransferase Homo sapiens 4-8 17187009-5 2006 The aim of our study was to assess whether the COMT gene Val158Met functional polymorphism in patients dependent on methamphetamine is related to their novelty seeking score. Methamphetamine 116-131 catechol-O-methyltransferase Homo sapiens 47-51 16829779-0 2006 An association study between catechol-O-methyl transferase gene polymorphism and methamphetamine psychotic disorder. Methamphetamine 81-96 catechol-O-methyltransferase Homo sapiens 29-58 16829779-6 2006 BASIC METHODS: We examined the functional polymorphism of val 158 met (catechol-O-methyl transferase) in 143 patients with methamphetamine psychosis and 200 healthy controls in Japan. Methamphetamine 123-138 catechol-O-methyltransferase Homo sapiens 71-100 16829779-10 2006 CONCLUSIONS: Our results indicate that the met allele frequency of the catechol-O-methyl transferase is associated with patients who experienced methamphetamine psychosis and spontaneous relapse, suggesting that patients with a met allele appear to be at increased risk of an adverse response to methamphetamine. Methamphetamine 145-160 catechol-O-methyltransferase Homo sapiens 71-100 16829779-10 2006 CONCLUSIONS: Our results indicate that the met allele frequency of the catechol-O-methyl transferase is associated with patients who experienced methamphetamine psychosis and spontaneous relapse, suggesting that patients with a met allele appear to be at increased risk of an adverse response to methamphetamine. Methamphetamine 296-311 catechol-O-methyltransferase Homo sapiens 71-100 24941367-2 2007 The aim of our study was to assess whether the catechol-O-methyltransferase (COMT) genetic background of patients dependent on metamphetamine is related to their non-abstinence in a 1-year follow-up. Methamphetamine 127-141 catechol-O-methyltransferase Homo sapiens 47-75 24941367-2 2007 The aim of our study was to assess whether the catechol-O-methyltransferase (COMT) genetic background of patients dependent on metamphetamine is related to their non-abstinence in a 1-year follow-up. Methamphetamine 127-141 catechol-O-methyltransferase Homo sapiens 77-81 32739643-0 2020 COMT val158met genotype alters the effects of methamphetamine dependence on dopamine and dopamine-related executive function: preliminary findings. Methamphetamine 46-61 catechol-O-methyltransferase Homo sapiens 0-4 27987399-0 2017 Association between cerebrospinal fluid dopamine concentrations and catechol-O-methyltransferase gene polymorphisms in forensic autopsy cases of methamphetamine abusers. Methamphetamine 145-160 catechol-O-methyltransferase Homo sapiens 68-96 31301644-0 2019 Adverse effect of catechol-O-methyltransferase (COMT) Val158Met met/met genotype in methamphetamine-related executive dysfunction. Methamphetamine 84-99 catechol-O-methyltransferase Homo sapiens 18-46 31301644-0 2019 Adverse effect of catechol-O-methyltransferase (COMT) Val158Met met/met genotype in methamphetamine-related executive dysfunction. Methamphetamine 84-99 catechol-O-methyltransferase Homo sapiens 48-52 20728009-2 2010 Catechol-O-methyltransferase (COMT) plays a vital role in dopamine inactivation, and the Val(158)Met single nucleotide polymorphism (rs4680) in its gene has been recently associated with the Novelty Seeking (NS) temperament scale of the Temperament and Character Inventory in studies of healthy adults, as well as methamphetamine abusers. Methamphetamine 314-329 catechol-O-methyltransferase Homo sapiens 0-28 21934638-0 2011 A COMT gene haplotype associated with methamphetamine abuse. Methamphetamine 38-53 catechol-O-methyltransferase Homo sapiens 2-6 21876500-2 2011 Dependence on methamphetamine is markedly related to the brain neurotransmitter dopamine, metabolised by catechol-O-methyltransferase enzyme. Methamphetamine 14-29 catechol-O-methyltransferase Homo sapiens 105-133 21876500-3 2011 The main aim of the study was to ascertain whether the Val158Met catechol-O-methyltransferase gene polymorphism is associated with methamphetamine dependence in this Central European country. Methamphetamine 131-146 catechol-O-methyltransferase Homo sapiens 65-93 20728009-2 2010 Catechol-O-methyltransferase (COMT) plays a vital role in dopamine inactivation, and the Val(158)Met single nucleotide polymorphism (rs4680) in its gene has been recently associated with the Novelty Seeking (NS) temperament scale of the Temperament and Character Inventory in studies of healthy adults, as well as methamphetamine abusers. Methamphetamine 314-329 catechol-O-methyltransferase Homo sapiens 30-34 24078782-0 2010 Impact of COMT Val158Met on executive functioning in the context of HIV and methamphetamine. Methamphetamine 76-91 catechol-O-methyltransferase Homo sapiens 10-14 20069120-0 2010 COMT Val158Met Polymorphism, Executive Dysfunction, and Sexual Risk Behavior in the Context of HIV Infection and Methamphetamine Dependence. Methamphetamine 113-128 catechol-O-methyltransferase Homo sapiens 0-4 19219857-7 2009 Three genes (COMT, DRD4, and GABRA1) were associated with METH abuse, nine (ARRB2, BDNF, CYP2D6, GLYT1, GSTM1, GSTP1, PDYN, PICK1, and SLC22A3) with METH dependence, two (AKT1 and GABRG2) with METH abuse/dependence, and four (DTNBP1, OPRM1, SNCA, and SOD2) with METH psychosis. Methamphetamine 58-62 catechol-O-methyltransferase Homo sapiens 13-17