PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33359793-7	2021	METH up-regulated inflammation-related factors, such as caspase1, TNF-alpha and IL-18, by activating the toll-like receptors 4 (TLR4)/myeloid differentiation factor 88 (Myd88)/nuclear factor kappaB (NF-kappaB) pathway and reduced occludin protein expression.	Methamphetamine	0-4	myeloid differentiation primary response gene 88	Mus musculus	169-174	
34381368-0	2021	Antibiotics Attenuate Methamphetamine-Induced Hepatotoxicity by Regulating Oxidative Stress and TLR4/MyD88/Traf6 Axis.	Methamphetamine	22-37	myeloid differentiation primary response gene 88	Mus musculus	101-106	
34381368-9	2021	Western blot analysis indicated that antibiotics inhibited the increase of TLR4, MyD88 and Traf6 induced by METH.	Methamphetamine	108-112	myeloid differentiation primary response gene 88	Mus musculus	81-86	
34381368-10	2021	This research suggests that antibiotics may play an important role in preventing METH-induced liver injury by regulating oxidative stress and TLR4/MyD88/Traf6 axis, though further investigation is required.	Methamphetamine	81-85	myeloid differentiation primary response gene 88	Mus musculus	147-152	
32941923-0	2021	Melatonin ameliorates methamphetamine-induced cognitive impairments by inhibiting neuroinflammation via suppression of the TLR4/MyD88/NFkappaB signaling pathway in the mouse hippocampus.	Methamphetamine	22-37	myeloid differentiation primary response gene 88	Mus musculus	128-133	
32768653-7	2020	Intriguingly, Peli1 upregulation induced by Meth was dependent on TRIF rather than the myloid differentiation factor 88 (MyD88) pathway, since the silencing of TRIF significantly suppressed Meth-induced Peli1 upregulation, while MyD88 knockdown had no obvious impact.	Methamphetamine	44-48	myeloid differentiation primary response gene 88	Mus musculus	229-234	
32768653-7	2020	Intriguingly, Peli1 upregulation induced by Meth was dependent on TRIF rather than the myloid differentiation factor 88 (MyD88) pathway, since the silencing of TRIF significantly suppressed Meth-induced Peli1 upregulation, while MyD88 knockdown had no obvious impact.	Methamphetamine	190-194	myeloid differentiation primary response gene 88	Mus musculus	229-234	
32941923-8	2021	METH-induced activation of glial cells is associated with the activation of the TLR4/MyD88/NFkappaB signaling pathway.	Methamphetamine	0-4	myeloid differentiation primary response gene 88	Mus musculus	85-90