PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33218491-9 2020 Via binding with a different pair of PA and PB, this suspension sensor array has successfully typed and quantified cancer-associated miRNAs of miR-21, miR-155, miR-335, and miR-122 in buffer and serum conditions. Protactinium 37-39 microRNA 21 Homo sapiens 143-149 34406744-6 2021 The probe demonstrated a ratiometric PA limit of detection of 148 pM miR-21, sequence specificity against one- and two-base mutations, and selectivity over other microRNAs. Protactinium 37-39 microRNA 21 Homo sapiens 69-75 34406744-7 2021 It was further tested in live human ovarian cancer (SKOV3) and noncancerous (HEK 293T) cells to exemplify in situ PA activation based on differences in endogenous miR-21 regulation (p = 0.0002). Protactinium 114-116 microRNA 21 Homo sapiens 163-169 34406744-9 2021 The probe"s miR-21-specific activation and its ability to maintain contrast in biologically relevant absorbing and scattering media support its consideration for live-cell PA microscopy and potential cancer diagnostics. Protactinium 172-174 microRNA 21 Homo sapiens 12-18 32717421-10 2020 Furthermore, overexpression of miR-21 improved the impaired mitochondrial biogenesis and decreased the cardiomyocyte apoptosis induced by HG/PA, while inhibition of miR-21 exerted the opposite effects. Protactinium 141-143 microRNA 21 Homo sapiens 31-37 30109002-3 2018 Here, we report the design, synthesis and binding of a peptidic-aminoglycoside (PA) based chemical library against pre-miR21 that led to the identification of a group of small molecules that bind to pre-miR21 with high affinities and antagonize miR-21 maturation and function, thereby reversing EMT. Protactinium 80-82 microRNA 21 Homo sapiens 119-124 30109002-3 2018 Here, we report the design, synthesis and binding of a peptidic-aminoglycoside (PA) based chemical library against pre-miR21 that led to the identification of a group of small molecules that bind to pre-miR21 with high affinities and antagonize miR-21 maturation and function, thereby reversing EMT. Protactinium 80-82 microRNA 21 Homo sapiens 203-208 30109002-3 2018 Here, we report the design, synthesis and binding of a peptidic-aminoglycoside (PA) based chemical library against pre-miR21 that led to the identification of a group of small molecules that bind to pre-miR21 with high affinities and antagonize miR-21 maturation and function, thereby reversing EMT. Protactinium 80-82 microRNA 21 Homo sapiens 245-251