PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31295033-6 2020 Immunofluorescence assay also showed that PAS could reduce phosphorylation of IGF-1R (Tyr1165/1166). Protactinium 42-45 insulin like growth factor 1 receptor Homo sapiens 78-84 29686616-5 2018 We demonstrated that estradiol treatment of adult PA exposed animals induced an increase in estrogen receptor (ER) alpha and insulin-like growth factor receptor (IGF-1R) protein levels, an activation of the phosphatidylinositol 3-kinase/Akt/glycogen synthase kinase 3 beta/beta-catenin signaling pathway and an increase in Bcl-2/Bax ratio in the hippocampus in comparison to PA exposed animals treated with vehicle. Protactinium 50-52 insulin like growth factor 1 receptor Homo sapiens 162-168 29686616-6 2018 Taking together, our data suggest that the interaction between ERalpha and IGF-IR, with the subsequent downstream activation, underlies the beneficial effects of estradiol observed in late treatment of PA. Protactinium 202-204 insulin like growth factor 1 receptor Homo sapiens 75-81 18693051-10 2009 By Western blot and ELISA, IR and IGF-IR were detected in PA, dPA and mAD. Protactinium 58-60 insulin like growth factor 1 receptor Homo sapiens 34-40