PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10917554-0	2000	Vinblastine and sulfinpyrazone export by the multidrug resistance protein MRP2 is associated with glutathione export.	Vinblastine	0-11	ATP binding cassette subfamily C member 2	Canis lupus familiaris	74-78	
12134946-5	2002	Apparent Michaelis-Menten constants (K(M), Vmax) for the efflux of vinblastine in Caco-2 and MDCK-MRP2 cells were determined in the presence of GF120918 (2 microM), which inhibits P-glycoprotein but does not affect MRP2.	Vinblastine	67-78	ATP binding cassette subfamily C member 2	Canis lupus familiaris	93-102	
12134946-5	2002	Apparent Michaelis-Menten constants (K(M), Vmax) for the efflux of vinblastine in Caco-2 and MDCK-MRP2 cells were determined in the presence of GF120918 (2 microM), which inhibits P-glycoprotein but does not affect MRP2.	Vinblastine	67-78	ATP binding cassette subfamily C member 2	Canis lupus familiaris	98-102	
12134946-6	2002	Apparent inhibitory constants (K(I)) of known substrates/inhibitors of MRP2 were determined by measuring their effects on the efflux of vinblastine in these cell lines.	Vinblastine	136-147	ATP binding cassette subfamily C member 2	Canis lupus familiaris	71-75	
12134946-10	2002	MDCK-MRP2 cell monolayers exhibited higher polarized efflux of vinblastine than Caco-2 and MDCK-WT cell monolayers.	Vinblastine	63-74	ATP binding cassette subfamily C member 2	Canis lupus familiaris	0-9	
12134946-11	2002	K(M) values for vinblastine in Caco-2 and MDCK-MRP2 cells were determined to be 71.8+/-11.6 and 137.3+/-33.6 microM.	Vinblastine	16-27	ATP binding cassette subfamily C member 2	Canis lupus familiaris	42-51	
10917554-4	2000	In these cells MRP1 transports daunorubicin, and MRP2 vinblastine; both transporters export reduced glutathione (GSH) into the medium.	Vinblastine	54-65	ATP binding cassette subfamily C member 2	Canis lupus familiaris	49-53	
10917554-8	2000	We also show that GSH export in MDCKII-MRP2 cells increases in the presence of vinblastine, and that the stoichiometry between drug and GSH exported is between two and three.	Vinblastine	79-90	ATP binding cassette subfamily C member 2	Canis lupus familiaris	39-43