PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19214144-7 2009 None of these mutations had any effect on MRP1/ABCC1 expression and trafficking, but that Arg723Gln mutation significantly reduced MRP1/ABCC1-mediated resistance to daunorubicin, doxorubicin, etoposide, vinblastine, and vincristine. Vinblastine 203-214 ATP binding cassette subfamily C member 1 Homo sapiens 131-135 24558228-12 2014 Functional analysis demonstrated that the skin absorptions of rhodamine 123, [3H]-vinblastine, and [3H]-LTC4 were markedly decreased in the presence of MRP1 inhibitors (verapamil and MK571), thus supporting the role of MRP1 in the uptake of compounds from the epidermal compartment as well as their secretion into the bloodstream and sweat ducts. Vinblastine 82-93 ATP binding cassette subfamily C member 1 Homo sapiens 152-156 17475454-1 2007 The mRNA level expression of MDR1, MRP1-6, BCRP and CYP3A4 was determined by quantitative PCR in wild type (Caco-2WT) and vinblastine-treated (Caco-2VBL) Caco-2 cells at different passage levels (32-53). Vinblastine 122-133 ATP binding cassette subfamily C member 1 Homo sapiens 35-41 18946672-4 2009 OBJECTIVE: To compare the expression profiles of the multidrug resistance genes ABCB1, ABCC1, and ABCG2 in different neuroepithelial pediatric brain tumor cell lines prior and following short-term culture with vinblastine. Vinblastine 210-221 ATP binding cassette subfamily C member 1 Homo sapiens 87-92 17118011-9 2006 These MDR transporters serve protective roles in oocytes and eggs, as demonstrated by sensitization of the oocytes to the maturation inhibitor, vinblastine, by MRP and PGP-specific transporter inhibitors. Vinblastine 144-155 ATP binding cassette subfamily C member 1 Homo sapiens 160-163 12425469-0 2002 Effect of organic isothiocyanates on the P-glycoprotein- and MRP1-mediated transport of daunomycin and vinblastine. Vinblastine 103-114 ATP binding cassette subfamily C member 1 Homo sapiens 61-65 12425469-3 2002 METHODS: The direct effect of ITCs on the 2-h cellular accumulation of daunomycin (DNM) and vinblastine (VBL), substrates for both P-gp and MRP1, were measured in sensitive and resistant MCF-7 cells and in PANC-1 cells. Vinblastine 92-103 ATP binding cassette subfamily C member 1 Homo sapiens 140-144 11504821-4 2001 An increase in the rate of accumulation of the MRP1 substrate calcein was observed following treatment with the organic anion/MRP1 inhibitor indomethacin, the Pgp inhibitors cyclosporin A (CsA) and vinblastine, as well as conditions of energy depletion. Vinblastine 198-209 ATP binding cassette subfamily C member 1 Homo sapiens 47-51 11323161-7 2001 MRP1 expression was studied in MCF-7 cells where the chemotherapeutic drug vinblastine and tert-butyl hydroquinone but not the MRP2 inducing agents described above acted as inducers. Vinblastine 75-86 ATP binding cassette subfamily C member 1 Homo sapiens 0-4 10725273-7 2000 The B/A flux of losartan was inhibited by cyclosporine and vinblastine, inhibitors of P-glycoprotein and MRP. Vinblastine 59-70 ATP binding cassette subfamily C member 1 Homo sapiens 105-108 11498353-6 1999 Since our initial discovery that P-glycoprotein binds to vinblastine photoaffinity analogs, many P-glycoprotein- and MRP-specific photoaffinity analogs have been developed. Vinblastine 57-68 ATP binding cassette subfamily C member 1 Homo sapiens 117-120 9405241-7 1997 Furthermore, a molar excess of LTC4, MK 571 or vinblastine inhibited the photoaffinity labeling of MRP with IAAQ in intact cells and plasma membranes. Vinblastine 47-58 ATP binding cassette subfamily C member 1 Homo sapiens 99-102 16960658-17 2007 THC significantly increased the sensitivity of vinblastine, mitoxantrone and etoposide in drug resistance KB-V-1, MCF7AdrVp3000 and MRP1-HEK 293 cells, respectively. Vinblastine 47-58 ATP binding cassette subfamily C member 1 Homo sapiens 132-136 15198509-7 2004 The rMRP1 transfected cells, like their human ortholog, can confer drug resistance to vinca alkaloid (vinblastine and vincristine) and anthracycline drugs (daunorubcin and doxorubicin), and the resistance conferred by the MRP1 can be partially abolished by the MRP-specific inhibitors. Vinblastine 102-113 ATP binding cassette subfamily C member 1 Homo sapiens 5-9 15198509-7 2004 The rMRP1 transfected cells, like their human ortholog, can confer drug resistance to vinca alkaloid (vinblastine and vincristine) and anthracycline drugs (daunorubcin and doxorubicin), and the resistance conferred by the MRP1 can be partially abolished by the MRP-specific inhibitors. Vinblastine 102-113 ATP binding cassette subfamily C member 1 Homo sapiens 5-8 14620511-5 2003 RESULTS: Considerable increases of vinblastine and doxorubicin accumulation in the cells overexpressing MRP1 and MRP2 in the presence of P85 were observed, although no statistically significant changes in drug accumulation in the parental cells were found. Vinblastine 35-46 ATP binding cassette subfamily C member 1 Homo sapiens 104-108