PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16800923-10	2006	Various concentrations (50, 75, 100 microg/ml) of bestatin combined with 10 nmol/L ATRA down-regulated the expression of c-Myc protein, which was negatively correlated with the NBT reduction activity of NB4 cells induced by 10 nmol/L ATRA alone or plus bestatin at various concentrations (r = -0.940, P = 0.017).	ubenimex	50-58	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	121-126	
16800923-10	2006	Various concentrations (50, 75, 100 microg/ml) of bestatin combined with 10 nmol/L ATRA down-regulated the expression of c-Myc protein, which was negatively correlated with the NBT reduction activity of NB4 cells induced by 10 nmol/L ATRA alone or plus bestatin at various concentrations (r = -0.940, P = 0.017).	ubenimex	253-261	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	121-126	
16800923-12	2006	It is concluded that an aminopeptidase inhibitor bestatin can potentiate ATRA-inducing differentiation of NB4 cells, possibly by down-regulating c-myc expression in synergy with ATRA.	ubenimex	49-57	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	145-150	
17147245-5	2006	100 microg/ml of ubenimex could enhance the NBT reduction activity induced by 10 nmol/L of ATRA, intensify the down-regulation of c-Myc protein expression and inhibit the phosphorylation of p38MAPK protein induced by 10 nmol/L of ATRA in NB4 cells.	ubenimex	17-25	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	130-135	
17147245-6	2006	CONCLUSIONS: Ubenimex could potentiate ATRA induced differentiation in APL cells, which may be correlated with the inhibition of p38 MAPK protein phosphorylation and regulation of c-Myc protein expression.	ubenimex	13-21	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	180-185