PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33126591-3 2020 Among the three compounds, the bestatin-SAHA hybrid P1 exhibited comparable even more potent inhibitory activity against HDAC1, HDAC6 and HDAC8 relative to the approved HDAC inhibitor SAHA. ubenimex 31-39 histone deacetylase 1 Homo sapiens 121-126 34031358-5 2021 In conclusion, epigenetic silencing of PEPT1 due to increased DNMT1 and HDAC1 expression plays a vital role in the poor response of CRC to ubenimex. ubenimex 139-147 histone deacetylase 1 Homo sapiens 72-77