PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28758123-11	2017	Bestatin (400 mug), an aminopeptidase-N inhibitor, significantly enhanced low-dose (25 mug/paw) aripiprazole-induced peripheral antinociception.	ubenimex	0-8	alanyl (membrane) aminopeptidase	Mus musculus	23-39	
30258365-5	2018	CD13 inhibitor, bestatin, enhances the antitumor effect of cytotoxic agents.	ubenimex	16-24	alanyl (membrane) aminopeptidase	Mus musculus	0-4	
33778075-13	2021	Conclusion: The bestatin treatment is suitable for suppressing the neoangiogenic process and APN/CD13 expression of experimental HT1080 and B16-F10 tumors; furthermore, 68Ga-NODAGA-c(NGR) is an applicable radiotracer for the in vivo monitoring of the efficacy of the APN/CD13 inhibition-based anticancer therapies.	ubenimex	16-24	alanyl (membrane) aminopeptidase	Mus musculus	93-96	
27322756-1	2016	We designed and synthesized a novel mutual prodrug, named BC-01 (3), by integrating ubenimex and Fluorouracil (5-FU) into one molecule based on prior research results that showed that a combination of the aminopeptidase N (CD13) inhibitor, ubenimex, and the cytotoxic antitumor agent, 5-FU, exhibited improved in vitro and in vivo antitumor efficiency.	ubenimex	84-92	alanyl (membrane) aminopeptidase	Mus musculus	205-221	
11931342-7	2002	Inhibition of aminopeptidase N by bestatin reduced writhing in both strains, whereas NEP-inhibition by thiorphan reduced writhing selectively in wild-type mice.	ubenimex	34-42	alanyl (membrane) aminopeptidase	Mus musculus	14-30	
17266036-8	2007	Subsequently, we found a significant increase in PAC-sensitivity of APN/CD13 expressing OVCA cells by suppression of this enzyme, using the addition of bestatin or the siRNA technique.	ubenimex	152-160	alanyl (membrane) aminopeptidase	Mus musculus	68-71	
17266036-8	2007	Subsequently, we found a significant increase in PAC-sensitivity of APN/CD13 expressing OVCA cells by suppression of this enzyme, using the addition of bestatin or the siRNA technique.	ubenimex	152-160	alanyl (membrane) aminopeptidase	Mus musculus	72-76	
15500947-1	2004	We investigated the effect of bestatin, an inhibitor of aminopeptidase N (APN)/CD13 and aminopeptidase B, on the angiogenesis induced by B16-BL6 melanoma cells.	ubenimex	30-38	alanyl (membrane) aminopeptidase	Mus musculus	56-72	
15500947-1	2004	We investigated the effect of bestatin, an inhibitor of aminopeptidase N (APN)/CD13 and aminopeptidase B, on the angiogenesis induced by B16-BL6 melanoma cells.	ubenimex	30-38	alanyl (membrane) aminopeptidase	Mus musculus	74-77	
15500947-1	2004	We investigated the effect of bestatin, an inhibitor of aminopeptidase N (APN)/CD13 and aminopeptidase B, on the angiogenesis induced by B16-BL6 melanoma cells.	ubenimex	30-38	alanyl (membrane) aminopeptidase	Mus musculus	79-83	
15500947-5	2004	These findings suggest that bestatin is an active anti-angiogenic agent that may inhibit tumor angiogenesis in vivo and tube-like formation of endothelial cells in vitro through its inhibition of APN/CD13 activity.	ubenimex	28-36	alanyl (membrane) aminopeptidase	Mus musculus	196-199	
15500947-5	2004	These findings suggest that bestatin is an active anti-angiogenic agent that may inhibit tumor angiogenesis in vivo and tube-like formation of endothelial cells in vitro through its inhibition of APN/CD13 activity.	ubenimex	28-36	alanyl (membrane) aminopeptidase	Mus musculus	200-204	
10844131-8	2000	A small reduction in [Leu(5)]enkephalin degradation was detected in striatal membrane preparations of NEP-/- mice, if aminopeptidase N was additionally blocked by bestatin or amastatin.	ubenimex	163-171	alanyl (membrane) aminopeptidase	Mus musculus	118-134	
33778075-13	2021	Conclusion: The bestatin treatment is suitable for suppressing the neoangiogenic process and APN/CD13 expression of experimental HT1080 and B16-F10 tumors; furthermore, 68Ga-NODAGA-c(NGR) is an applicable radiotracer for the in vivo monitoring of the efficacy of the APN/CD13 inhibition-based anticancer therapies.	ubenimex	16-24	alanyl (membrane) aminopeptidase	Mus musculus	267-270