PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
18336632-3	2008	The present study investigates the effects of ethanol on the human peptide transporter 1 (hPepT1) which mediates the transport of di-and tripeptides as well as several orally administered peptidomimetic drugs such as beta-lactam antibiotics (e.g., penicillin), angiotensin-converting enzyme inhibitors, the anti-neoplastic agent bestatin, and prodrugs of acyclovir.	ubenimex	329-337	solute carrier family 15 member 1	Homo sapiens	90-96	
34031358-1	2021	Human intestinal peptide transporter PEPT1 is commonly repressed in human colorectal cancer (CRC), yet its relationship with sensitivity to the common CRC treatment ubenimex has not previously been elucidated.	ubenimex	165-173	solute carrier family 15 member 1	Homo sapiens	37-42	
34031358-4	2021	Finally, the effects of the epigenetic activation of PEPT1 on the CRC response to ubenimex were evaluated using sequential combination therapy of decitabine and ubenimex both in vitro and in xenografts.	ubenimex	82-90	solute carrier family 15 member 1	Homo sapiens	53-58	
34031358-5	2021	In conclusion, epigenetic silencing of PEPT1 due to increased DNMT1 and HDAC1 expression plays a vital role in the poor response of CRC to ubenimex.	ubenimex	139-147	solute carrier family 15 member 1	Homo sapiens	39-44	
28214542-5	2017	For this, we selected the common orally administered drugs sulpiride, bestatin, valacyclovir, ampicillin and oseltamivir, that are all transported by hPepT1.	ubenimex	70-78	solute carrier family 15 member 1	Homo sapiens	150-156	
25016073-4	2014	Bestatin and cefixime can mutually competitively inhibit the uptake by hPEPT1-HeLa cells.	ubenimex	0-8	solute carrier family 15 member 1	Homo sapiens	71-77	
25016073-10	2014	PEPT1 and OAT1/3 are the target transporters of DDIs between bestatin and cefixime in human kidney slices and human transfected cells, proposing possible drug-drug interaction in humans.	ubenimex	61-69	solute carrier family 15 member 1	Homo sapiens	0-5	
12816347-5	2003	Drug molecules such as oral active beta-lactam antibiotics, bestatin, prodrugs of aciclovir and ganciclovir have oral bioavailabilities, which largely are a result of their interaction with PepT1.	ubenimex	60-68	solute carrier family 15 member 1	Homo sapiens	190-195	
16627568-7	2006	Our results indicate that the substrate selectivity of hPEPT1 is: Gly-Sar > NAAG, delta-ALA, bestatin > cefadroxil, cephalexin > ampicillin, amoxicillin.	ubenimex	96-104	solute carrier family 15 member 1	Homo sapiens	55-61	
11004680-1	2000	To study the drug delivery to tumor by utilization of an oligopeptide transport activity, we examined the accumulation of dipeptides and the peptide-mimetic anti-cancer drug, bestatin, a substrate of oligopeptide transporter PepT1.	ubenimex	175-183	solute carrier family 15 member 1	Homo sapiens	225-230