PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29069816-6 2017 Ubenimex inhibits the expression of the proto-oncogene, Pim-3, which is accompanied by decreased expression of BCL-2 and BCL-XL, decreased phosphorylation of Bad, and increased tumor apoptosis. ubenimex 0-8 BCL2 apoptosis regulator Homo sapiens 111-116 30915355-6 2019 Moreover, Ubenimex reverses the MDR of SGC7901/X and MKN45/X cells and enhances their sensitivity to FOLFOX, in part by decreasing CD13 expression, which is accompanied by downregulation of Bcl-xl, Bcl-2, and survivin expression; increased expression of Bax; and activation of the caspase-3-mediated apoptotic cascade. ubenimex 10-18 BCL2 apoptosis regulator Homo sapiens 198-203