PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25047426-0	2014	Hesperidin induces apoptosis and triggers autophagic markers through inhibition of Aurora-A mediated phosphoinositide-3-kinase/Akt/mammalian target of rapamycin and glycogen synthase kinase-3 beta signalling cascades in experimental colon carcinogenesis.	Hesperidin	0-10	aurora kinase A	Homo sapiens	83-91	
25047426-4	2014	In the present study, we aimed at investigating the potential of hesperidin over the abrogated Aurora-A coupled pro-survival phosphoinositide-3-kinase (PI3K)/Akt signalling cascades.	Hesperidin	65-75	aurora kinase A	Homo sapiens	95-103	
25047426-12	2014	Aurora-A an upstream regulator of PI3K/Akt pathway was significantly inhibited by hesperidin.	Hesperidin	82-92	aurora kinase A	Homo sapiens	0-8	
25047426-14	2014	Taken together, hesperidin supplementation initiated apoptosis via targeted inhibition of constitutively activated Aurora-A mediated PI3K/Akt/GSK-3beta and mTOR pathways coupled with autophagic stimulation against AOM induced colon carcinogenesis.	Hesperidin	16-26	aurora kinase A	Homo sapiens	115-123