PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34575098-7 2021 We demonstrated that the expression of CYC1, TFAM, ATP5PB, mtATP6, mtDNA, and NRF-1 were decreased upon 12 h treatment, and subsequent ATP production was also significantly decreased at 24 h. These results identified a synergistic effect induced by combinational treatment with hesperidin and chlorogenic acid, which can regulate mitochondria and ATP production through the estrogen receptor pathway in MCF-7 cells. Hesperidin 278-288 mitochondrially encoded ATP synthase 6 Homo sapiens 59-65