PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32164488-6	2020	The levels of IL-6, IL-8, and MDA in BLAF and pulmonary MPO content in the COPD mice were effectively increased, while the levels of SOD and CAT in BLAF were decreased, which could be reversed by budesonide and hesperidin.	Hesperidin	211-221	interleukin 6	Mus musculus	14-18	
34721041-11	2021	Results: Compared with the ATO group, the HES treatment groups reduced the levels of CK, LDH, cTnI, ROS, MDA, TNF-alpha, IL-6, Bax, Caspase-3, cleaved-Caspase-3 and Keap1 and enhanced the levels of SOD, GSH, CAT, Bcl-2, p62 and Nrf2.	Hesperidin	42-45	interleukin 6	Mus musculus	121-125	
27182608-3	2016	Hesperidin, eriocitrin and eriodictyol increased the serum total antioxidant capacity, and restrained the elevation of interleukin-6 (IL-6), macrophage chemoattractant protein-1 (MCP-1), and C-reactive protein (hs-CRP).	Hesperidin	0-10	interleukin 6	Mus musculus	119-132	
27182608-3	2016	Hesperidin, eriocitrin and eriodictyol increased the serum total antioxidant capacity, and restrained the elevation of interleukin-6 (IL-6), macrophage chemoattractant protein-1 (MCP-1), and C-reactive protein (hs-CRP).	Hesperidin	0-10	interleukin 6	Mus musculus	134-138	
21434774-7	2011	The concentration of serum cytokines (interleukin-1beta, interleukin-6, and tumor necrosis factor-alpha) decreased in the radiation group treated with hesperidin at 50 and 200 mg/kg of body weight compared with the control group on Day 10 after irradiation.	Hesperidin	151-161	interleukin 6	Mus musculus	57-103	
29115547-7	2018	Hesperidin treatment caused a significant decrease in the levels of TNF-alpha, IL-1beta, IL-6, MCP-1, ICAM-1, MDA, CAT, SOD and caspase-3/9 in mice with AMI.	Hesperidin	0-10	interleukin 6	Mus musculus	89-93	
19386481-6	2009	Oral administration of Hesperidin significantly decreased DAI, MPO activity, MDA content and the level of IL-6 in serum (p<0.01), while there was no significantly effect on the level of IL-4 in serum.	Hesperidin	23-33	interleukin 6	Mus musculus	106-110	
35332348-10	2022	HES also reduced the CP-induced release of the inflammatory factors tumour necrosis factor (TNF)-alpha and interleukin (IL)-6.	Hesperidin	0-3	interleukin 6	Mus musculus	107-125