PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25135708-6	2014	Furthermore, Glycogen synthase kinase-3beta (GSK-3beta) phosphorylation significantly increased in the hesperidin-treated (100 mg/kg per day) group.	Hesperidin	103-113	glycogen synthase kinase 3 alpha	Mus musculus	45-54	
25135708-7	2014	Taken together, these findings suggest that a reduction in mitochondrial dysfunction through the inhibition of GSK-3beta activity, coupled with an increase in anti-oxidative defense, may be one of the mechanisms by which hesperidin improves cognitive function in the APPswe/PS1dE9 transgenic mouse model of AD.	Hesperidin	221-231	glycogen synthase kinase 3 alpha	Mus musculus	111-120