PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30817082-7	2019	Hesperidin also obviously upregulates Nrf2 antioxidant pathway and increases the protein expression of HO-1 and NQO1.	Hesperidin	0-10	NFE2 like bZIP transcription factor 2	Homo sapiens	38-42	
34583226-5	2021	We found that the phytochemical compounds, such as curcumin, naringenin, sulforaphane, diallyl disulfide, mangiferin, oleanolic acid, umbelliferone, daphnetin, quercetin, isorhamnetin-3-O-galactoside, hesperidin, diammonium glycyrrhizinate, corilagin, shikonin, farrerol, and chenpi, had the potential to improve the Nrf2-ARE signaling thereby combat hepatotoxicity.	Hesperidin	201-211	NFE2 like bZIP transcription factor 2	Homo sapiens	317-321	
30817082-12	2019	CONCLUSION: Hesperidin can protect against intestinal inflammation via enhanced Nrf2 antioxidant pathway, increases the Treg population, and restores intestinal barrier function.	Hesperidin	12-22	NFE2 like bZIP transcription factor 2	Homo sapiens	80-84	
20678535-7	2010	Western blot showed that hesperidin facilitated ERK/MAPK phosphorylation which appeared to be responsible for nuclear translocation of Nrf2, thereby inducing cytoprotective heme oxygenase-1 (HO-1) expression.	Hesperidin	25-35	NFE2 like bZIP transcription factor 2	Homo sapiens	135-139	
20170153-5	2010	In addition, hesperidin also promoted nuclear translocation of nuclear factor erythroid 2-related factor (Nrf2).	Hesperidin	13-23	NFE2 like bZIP transcription factor 2	Homo sapiens	63-104	
20170153-5	2010	In addition, hesperidin also promoted nuclear translocation of nuclear factor erythroid 2-related factor (Nrf2).	Hesperidin	13-23	NFE2 like bZIP transcription factor 2	Homo sapiens	106-110	
20170153-8	2010	Taken together, the above findings suggested that hesperidin augmented cellular antioxidant defense capacity through the induction of HO-1 via ERK/Nrf2 signaling.	Hesperidin	50-60	NFE2 like bZIP transcription factor 2	Homo sapiens	147-151