PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30817082-7 2019 Hesperidin also obviously upregulates Nrf2 antioxidant pathway and increases the protein expression of HO-1 and NQO1. Hesperidin 0-10 NFE2 like bZIP transcription factor 2 Homo sapiens 38-42 30817082-12 2019 CONCLUSION: Hesperidin can protect against intestinal inflammation via enhanced Nrf2 antioxidant pathway, increases the Treg population, and restores intestinal barrier function. Hesperidin 12-22 NFE2 like bZIP transcription factor 2 Homo sapiens 80-84 20678535-7 2010 Western blot showed that hesperidin facilitated ERK/MAPK phosphorylation which appeared to be responsible for nuclear translocation of Nrf2, thereby inducing cytoprotective heme oxygenase-1 (HO-1) expression. Hesperidin 25-35 NFE2 like bZIP transcription factor 2 Homo sapiens 135-139 34583226-5 2021 We found that the phytochemical compounds, such as curcumin, naringenin, sulforaphane, diallyl disulfide, mangiferin, oleanolic acid, umbelliferone, daphnetin, quercetin, isorhamnetin-3-O-galactoside, hesperidin, diammonium glycyrrhizinate, corilagin, shikonin, farrerol, and chenpi, had the potential to improve the Nrf2-ARE signaling thereby combat hepatotoxicity. Hesperidin 201-211 NFE2 like bZIP transcription factor 2 Homo sapiens 317-321 20170153-5 2010 In addition, hesperidin also promoted nuclear translocation of nuclear factor erythroid 2-related factor (Nrf2). Hesperidin 13-23 NFE2 like bZIP transcription factor 2 Homo sapiens 63-104 20170153-5 2010 In addition, hesperidin also promoted nuclear translocation of nuclear factor erythroid 2-related factor (Nrf2). Hesperidin 13-23 NFE2 like bZIP transcription factor 2 Homo sapiens 106-110 20170153-8 2010 Taken together, the above findings suggested that hesperidin augmented cellular antioxidant defense capacity through the induction of HO-1 via ERK/Nrf2 signaling. Hesperidin 50-60 NFE2 like bZIP transcription factor 2 Homo sapiens 147-151