PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23469045-3 2013 In combination with carbachol (10 microM), rivastigmine (1 microM) significantly decreased the release of nitric oxide, TNF-alpha, IL-1beta and IL-6 from lipopolysaccharide-activated RAW 264.7 macrophages and this effect was abolished by alpha7 nicotinic receptor blockade by bungarotoxin. Carbachol 20-29 tumor necrosis factor Rattus norvegicus 120-129 8679222-4 1996 In a similar manner, selective TNF alpha-p55 receptor agonists such as htr-9, an activating monoclonal antibody, or a recombinant TNF-p55 (rTNF-p55), which specifically activates the TNF alpha-p55 receptor but not the TNF alpha-p75 receptor, also augmented [Ca2+]i transients evoked by carbachol. Carbachol 286-295 tumor necrosis factor Rattus norvegicus 31-34 8679222-4 1996 In a similar manner, selective TNF alpha-p55 receptor agonists such as htr-9, an activating monoclonal antibody, or a recombinant TNF-p55 (rTNF-p55), which specifically activates the TNF alpha-p55 receptor but not the TNF alpha-p75 receptor, also augmented [Ca2+]i transients evoked by carbachol. Carbachol 286-295 tumor necrosis factor Rattus norvegicus 139-143 24377382-9 2013 However, combination of Cch with other mitogens exhibited a dual effect, synergistic proliferation effect in the presence of EGF (5 ng/mL) and 5% FBS and inhibiting the proliferation induced by 10% FBS, EGF (10 ng/mL) and TNF-alpha (10 ng/mL). Carbachol 24-27 tumor necrosis factor Rattus norvegicus 222-231 20871620-0 2010 Carbachol inhibits TNF-alpha-induced endothelial barrier dysfunction through alpha 7 nicotinic receptors. Carbachol 0-9 tumor necrosis factor Rattus norvegicus 19-28 20805763-8 2011 RESULTS: Carbachol inhibited expression of TNF-alpha and IL-6 after LPS injection and had no significant effect on IL-10 in rat endotoxemia model. Carbachol 9-18 tumor necrosis factor Rattus norvegicus 43-52 20805763-10 2011 Cell experiments also showed that increases of TNF-alpha and IL-6 after LPS stimulation could be significantly inhibited by carbachol or nicotine, whereas IL-10 was not apparently altered. Carbachol 124-133 tumor necrosis factor Rattus norvegicus 47-56 20871620-6 2010 RESULTS: Carbachol (2 mumol/L-2 mmol/L) prevented increase in endothelial cell permeability induced by TNF-alpha (500 ng/mL) in a dose-dependent manner. Carbachol 9-18 tumor necrosis factor Rattus norvegicus 103-112 20871620-10 2010 CONCLUSION: These data suggest that the inhibitory effect of carbachol on TNF-alpha-induced endothelial barrier dysfunction mediated by the alpha 7 nicotinic receptor. Carbachol 61-70 tumor necrosis factor Rattus norvegicus 74-83 19005736-6 2009 The increase in IP accumulation induced by CCh after TNF-alpha immersion was reduced in the BSMCs by LLLT. Carbachol 43-46 tumor necrosis factor Rattus norvegicus 53-62 16093422-4 2005 Pretreatment with TNF-alpha (100 ng/ml) hyperpolarized the membrane (from -31.0 +/- 2.7 mV under control conditions to -61.2 +/- 3.2 mV in the presence of the cytokine) and potentiated the depolarization induced by carbachol (from 5.2 +/- 0.7 mV under control conditions to 27.5 +/- 2.0 mV in the presence of the cytokine). Carbachol 215-224 tumor necrosis factor Rattus norvegicus 18-27 18768927-3 2008 The present study demonstrates that chronic exposure of polarized rat parotid gland (Par-C10) epithelial cell monolayers to TNF-alpha and IFN-gamma decreases transepithelial resistance (TER) and anion secretion, as measured by changes in short-circuit current (I(sc)) induced by carbachol, a muscarinic cholinergic receptor agonist, or UTP, a P2Y(2) nucleotide receptor agonist. Carbachol 279-288 tumor necrosis factor Rattus norvegicus 124-133 16879498-10 2006 Tissue incubation with TNF-alpha (100 ng ml(-1))/IL-1beta (10 ng ml(-1)) increased in vitro tracheal responsiveness to carbachol. Carbachol 119-128 tumor necrosis factor Rattus norvegicus 23-32 15086448-5 2004 The depolarization evoked by carbachol (50 microm) was potentiated from 5.2 +/- 0.7 mV (n = 6) in control neurones to 27.5 +/- 2.0 mV (n = 10) in TNF-alpha-treated cells. Carbachol 29-38 tumor necrosis factor Rattus norvegicus 146-155 14764222-1 2004 OBJECTIVE: To investigate the effects of carbachol injection in intestine on plasma levels of tumor necrosis factor-alpha(TNF-alpha), interleukin-10 (IL-10) and cortisol in rats during gut ischemia/reperfusion. Carbachol 41-50 tumor necrosis factor Rattus norvegicus 122-131 14764222-5 2004 RESULTS: The plasma levels of TNF-alpha significantly decreased in pretreated and treated groups than those in controls after carbachol injection (both P<0.01). Carbachol 126-135 tumor necrosis factor Rattus norvegicus 30-39 12831623-0 2003 [Effects of carbachol on plasma levels of tumor necrosis factor-alpha and interleukin-10 in rats during gut ischemia-reperfusion]. Carbachol 12-21 tumor necrosis factor Rattus norvegicus 42-69 12831623-1 2003 OBJECTIVE: To investigate the effects of carbachol on the levels of tumor necrosis factor-alpha (TNF-alpha), interleukin-10 (IL-10) and cortisol in plasma of rats during gut ischemia-reperfusion. Carbachol 41-50 tumor necrosis factor Rattus norvegicus 68-95 12831623-1 2003 OBJECTIVE: To investigate the effects of carbachol on the levels of tumor necrosis factor-alpha (TNF-alpha), interleukin-10 (IL-10) and cortisol in plasma of rats during gut ischemia-reperfusion. Carbachol 41-50 tumor necrosis factor Rattus norvegicus 97-106 12831623-6 2003 The levels of TNF-alpha significantly decreased in pretreated and treated groups than that in control after the intramuscular injection of carbachol (all P<0.01). Carbachol 139-148 tumor necrosis factor Rattus norvegicus 14-23