PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11939793-5 2002 The basal and carbachol-stimulated shedding of APP and ACE from human SH-SY5Y neuroblastoma cells could not be differentiated by any of the hydroxamate compounds, implying that the same or very similar activities are involved in the constitutive and regulated shedding of these two proteins. Carbachol 14-23 angiotensin I converting enzyme Homo sapiens 55-58 12799421-3 2003 In both cell types, GPI-ACE, but not WT-ACE, was sequestered in caveolin or flotillin-enriched lipid rafts and was released from the cell surface by treatment with phosphatidylinositol-specific phospholipase C. When cells were treated with activators of the protein kinase C signalling cascade (phorbol myristate acetate or carbachol) the shedding of GPI-ACE was stimulated to a similar extent to that of WT-ACE. Carbachol 324-333 angiotensin I converting enzyme Homo sapiens 24-27