PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 1443219-1 1992 In conscious, unrestrained rats, the intracerebroventricular injection of the cholinergic agonist, carbachol, or angiotensin II resulted in the transient stimulation of vasopressin secretion, elevation of mean arterial blood pressure, and reduction of heart rate. Carbachol 99-108 arginine vasopressin Rattus norvegicus 169-180 1443219-2 1992 After the injection of carbachol (25 ng) into a lateral cerebral ventricle, the plasma vasopressin concentration in male rats was increased to twice that of female rats in each phase of the estrous cycle; mean arterial blood pressure was elevated more in males than females, whereas heart rate fell to the same extent in both sexes. Carbachol 23-32 arginine vasopressin Rattus norvegicus 87-98 1450914-0 1992 Central carbachol stimulates vasopressin release into interstitial fluid adjacent to the paraventricular nucleus. Carbachol 8-17 arginine vasopressin Rattus norvegicus 29-40 1450914-1 1992 We have used an in vivo double microdialysis probe technique in conscious rats to determine whether the application of carbachol to one paraventricular nucleus (PVN) can result in increased local release of vasopressin from that PVN. Carbachol 119-128 arginine vasopressin Rattus norvegicus 207-218 1450914-4 1992 When carbachol (100 micrograms/ml) was included in the perfusate of one probe for the first 10 min of a 30-min collection period, while the other probe continued to be perfused with saline alone, there was a seven-fold increase in the concentration of vasopressin in the dialysate from the carbachol-perfused probe; the vasopressin concentration in the dialysate from the contralateral probe increased only slightly. Carbachol 5-14 arginine vasopressin Rattus norvegicus 252-263 1450914-4 1992 When carbachol (100 micrograms/ml) was included in the perfusate of one probe for the first 10 min of a 30-min collection period, while the other probe continued to be perfused with saline alone, there was a seven-fold increase in the concentration of vasopressin in the dialysate from the carbachol-perfused probe; the vasopressin concentration in the dialysate from the contralateral probe increased only slightly. Carbachol 5-14 arginine vasopressin Rattus norvegicus 320-331 1450914-6 1992 When one of the paired probes was perfused with carbachol (100 micrograms/ml) for 30 min, there were similar increases in the concentration of vasopressin in the dialysate from both probes and a sustained increase in the plasma vasopressin concentration. Carbachol 48-57 arginine vasopressin Rattus norvegicus 143-154 1450914-6 1992 When one of the paired probes was perfused with carbachol (100 micrograms/ml) for 30 min, there were similar increases in the concentration of vasopressin in the dialysate from both probes and a sustained increase in the plasma vasopressin concentration. Carbachol 48-57 arginine vasopressin Rattus norvegicus 228-239 2737706-4 1989 Intravenous vasopressin antagonist, d(CH2)5Tyr(Me) arginine vasopressin, significantly attenuated the pressor response and eliminated the bradycardic response to carbachol in Long-Evans rats. Carbachol 162-171 arginine vasopressin Rattus norvegicus 12-23 1877699-2 1991 The intracerebroventricular (icv) administration of carbachol (25 ng) resulted in marked transient increases in the plasma vasopressin concentration and mean arterial blood pressure and a transient reduction in heart rate. Carbachol 52-61 arginine vasopressin Rattus norvegicus 123-134 2804646-2 1989 injections (10 microliters) of carbachol (1.4 nmol), angiotensin II (AII; 48.2 pmol) or a hypertonic solution (990 mOsm/kg) produced increases of plasma vasopressin (AVP) and arterial pressure. Carbachol 31-40 arginine vasopressin Rattus norvegicus 153-164 2546748-7 1989 Moreover, naloxone (0.5 mg/kg) significantly increased AVP secretion induced by intracerebroventricular injection of carbachol (10 ng). Carbachol 117-126 arginine vasopressin Rattus norvegicus 55-58 2737706-4 1989 Intravenous vasopressin antagonist, d(CH2)5Tyr(Me) arginine vasopressin, significantly attenuated the pressor response and eliminated the bradycardic response to carbachol in Long-Evans rats. Carbachol 162-171 arginine vasopressin Rattus norvegicus 60-71 2737706-7 1989 Combined intravenous treatment with phentolamine and vasopressin antagonist completely eliminated the pressor response to carbachol in Long-Evans rats. Carbachol 122-131 arginine vasopressin Rattus norvegicus 53-64 2737706-10 1989 Hypertensive response to intracerebroventricularly administered carbachol in normal rats is mediated both by an increase in central sympathetic outflow and in circulating vasopressin. Carbachol 64-73 arginine vasopressin Rattus norvegicus 171-182 3342763-5 1988 Intracerebroventricular administration of leumorphin (600 pmol) also reduced the AVP secretion stimulated by icv injection of carbachol (50 pmol). Carbachol 126-135 arginine vasopressin Rattus norvegicus 81-84 2566191-6 1989 In contrast, vasopressin in concentrations as low as 0.025-0.25 U/liter decreased the secretory effects of EFS (55-75%) and carbachol (85%), but had no effect on cAMP-dependent secretion elicited either by VIP or forskolin. Carbachol 124-133 arginine vasopressin Rattus norvegicus 13-24 3359107-0 1988 Central inhibition by gamma-aminobutyric acid of the release of vasopressin by carbachol in the rat. Carbachol 79-88 arginine vasopressin Rattus norvegicus 64-75 3359107-2 1988 gamma-Aminobutyric acid (GABA) inhibited the antidiuretic response and the increased urinary excretion of vasopressin produced by carbachol when both drugs were injected into a lateral cerebral ventricle (i.c.v.) Carbachol 130-139 arginine vasopressin Rattus norvegicus 106-117 738215-0 1978 Vasopressin release from incubated in situ posterior pituitary lobe after intraventricular injection of carbachol or atropine. Carbachol 104-113 arginine vasopressin Rattus norvegicus 0-11 2874742-1 1986 Intracerebroventricular (icv) administration of carbachol into conscious rats evoked a substantial increase in vasopressin secretion and blood pressure in a dose-dependent manner. Carbachol 48-57 arginine vasopressin Rattus norvegicus 111-122 6088825-7 1984 These results indicate that carbachol injected intracerebroventricularly produces vasopressor effects mainly by releasing pituitary hormones, probably vasopressin, and that augmented pressor responses in SHR may be due to excessive release of vasopressin. Carbachol 28-37 arginine vasopressin Rattus norvegicus 151-162 6088825-7 1984 These results indicate that carbachol injected intracerebroventricularly produces vasopressor effects mainly by releasing pituitary hormones, probably vasopressin, and that augmented pressor responses in SHR may be due to excessive release of vasopressin. Carbachol 28-37 arginine vasopressin Rattus norvegicus 243-254 6694115-11 1984 injections of carbachol were due to increased sympathetic activity and vasopressin release. Carbachol 14-23 arginine vasopressin Rattus norvegicus 71-82 41059-9 1979 Betsamide antagonized the contractile effects of carbachol and 5-hydroxytryptamine on the rat vas deferens, but not the beta-responses of the guinea-pig trachea to adrenaline and isoproenaline. Carbachol 49-58 arginine vasopressin Rattus norvegicus 94-97 216539-2 1978 Carbamylcholine inhibited somewhat the vasopressin depletion in the neurohypophysis, but not earlier than under severe dehydration (8th and 12th day). Carbachol 0-15 arginine vasopressin Rattus norvegicus 39-50 3242998-3 1988 Intravenous vasopressin antagonist, d(CH2)5 Tyr(Me)AVP, significantly attenuated the pressor response and eliminated the bradycardic response to carbachol in LE rats. Carbachol 145-154 arginine vasopressin Rattus norvegicus 12-23 3242998-7 1988 carbachol in normal rats is mediated both by an increase in central sympathetic outflow and in circulating vasopressin. Carbachol 0-9 arginine vasopressin Rattus norvegicus 107-118 6694115-6 1984 However, in rats infused with carbachol for 2 or 5 days, the vasopressin levels were not significantly different from controls. Carbachol 30-39 arginine vasopressin Rattus norvegicus 61-72 738215-3 1978 The increase in the release of vasopressin following intracarotid infusions of hypertonic solution augmented by intraventricular injection of carbachol was found. Carbachol 142-151 arginine vasopressin Rattus norvegicus 31-42 738215-5 1978 The effects of carbachol and atropine indicate that mediation at synapses in the nucleus supraopticus involved in the release of vasopressin induced by osmotic stimulation is cholinergic. Carbachol 15-24 arginine vasopressin Rattus norvegicus 129-140 5104566-0 1971 Release of oxytocin and vasopressin in lactating rats after injection of carbachol into the third ventricle. Carbachol 73-82 arginine vasopressin Rattus norvegicus 24-35 868526-0 1977 Content of vasopressin in the neurohypophysis of long-term dehydrated rats as influenced by carbachol treatment. Carbachol 92-101 arginine vasopressin Rattus norvegicus 11-22 868526-1 1977 Content of vasopressin in the neurohypophysis of long-term dehydrated rats as influenced by carbachol treatment. Carbachol 92-101 arginine vasopressin Rattus norvegicus 11-22 868526-5 1977 Under extreme dehydration (8 and 12 days) the vasopressin depletion in the neurohypophysis was significantly inhibited in the carbachol-treated animals. Carbachol 126-135 arginine vasopressin Rattus norvegicus 46-57 962435-1 1976 Desensitization of the isolated rat vas deferens was demonstrated by using noradrenaline, 5-hydroxytryptamine, carbachol, acetylcholine or barium chloride as a test concentration after a large concentration (concentration producing a contraction that was 80% of the maximum) of the same agonist. Carbachol 111-120 arginine vasopressin Rattus norvegicus 36-39 26879866-9 2016 Plasma vasopressin levels evaluated by ELISA kit assay increased after carbachol into the 4th V. Intravenous blockade of V1 receptors prior to carbachol into the 4thV abolished the increase in IP evoked by carbachol. Carbachol 71-80 arginine vasopressin Rattus norvegicus 7-18 5767890-4 1969 In addition, these units are excited by intracarotid injections of carbachol, acetylcholine and NaCl (5%) which are less effective stimuli for vasopressin release.3. Carbachol 67-76 arginine vasopressin Rattus norvegicus 143-154 26879866-9 2016 Plasma vasopressin levels evaluated by ELISA kit assay increased after carbachol into the 4th V. Intravenous blockade of V1 receptors prior to carbachol into the 4thV abolished the increase in IP evoked by carbachol. Carbachol 143-152 arginine vasopressin Rattus norvegicus 7-18 26879866-9 2016 Plasma vasopressin levels evaluated by ELISA kit assay increased after carbachol into the 4th V. Intravenous blockade of V1 receptors prior to carbachol into the 4thV abolished the increase in IP evoked by carbachol. Carbachol 143-152 arginine vasopressin Rattus norvegicus 7-18 26879866-10 2016 Therefore, our findings suggest that cholinergic activation of neurons in the medulla oblongata by carbachol injections into the 4thV increases IP due to plasma vasopressin release, which acts in V1 receptors in the UB. Carbachol 99-108 arginine vasopressin Rattus norvegicus 161-172 27555117-4 2016 The bradycardia following the microinjection of CCh into the PHN can be attenuated by the previous administration of the vasopressin V1 receptor antagonist [d(CH2 )5 Tyr(Me)] arginine vasopressin (AVPX). Carbachol 48-51 arginine vasopressin Rattus norvegicus 121-132 27555117-4 2016 The bradycardia following the microinjection of CCh into the PHN can be attenuated by the previous administration of the vasopressin V1 receptor antagonist [d(CH2 )5 Tyr(Me)] arginine vasopressin (AVPX). Carbachol 48-51 arginine vasopressin Rattus norvegicus 184-195 27555117-6 2016 The attenuation by AVPX of the bradycardia that results following the high doses of CCh suggests that AVP is released into the circulation following stimulation of cholinergic systems within the PHN. Carbachol 84-87 arginine vasopressin Rattus norvegicus 19-22 27555117-7 2016 Thus, microinjection of a high dose of CCh (11 nmol) into the PHN alters the sensitivity of the baroreceptor reflex by increasing peripheral levels of AVP. Carbachol 39-42 arginine vasopressin Rattus norvegicus 151-154 21466795-1 2011 Microinjection of the cholinergic agonist carbachol into the bed nucleus of the stria terminalis (BST) has been reported to cause pressor response in unanesthetized rats, which was shown to be mediated by an acute release of vasopressin into the systemic circulation and followed by baroreflex-mediated bradycardia. Carbachol 42-51 arginine vasopressin Rattus norvegicus 225-236 21466795-5 2011 Moreover, BST treatment with carbachol significantly increased plasma vasopressin levels, thus confirming previous evidences that carbachol microinjection into the BST evokes pressor response due to vasopressin release into the circulation. Carbachol 29-38 arginine vasopressin Rattus norvegicus 70-81 21466795-5 2011 Moreover, BST treatment with carbachol significantly increased plasma vasopressin levels, thus confirming previous evidences that carbachol microinjection into the BST evokes pressor response due to vasopressin release into the circulation. Carbachol 29-38 arginine vasopressin Rattus norvegicus 199-210 21466795-5 2011 Moreover, BST treatment with carbachol significantly increased plasma vasopressin levels, thus confirming previous evidences that carbachol microinjection into the BST evokes pressor response due to vasopressin release into the circulation. Carbachol 130-139 arginine vasopressin Rattus norvegicus 70-81 21466795-5 2011 Moreover, BST treatment with carbachol significantly increased plasma vasopressin levels, thus confirming previous evidences that carbachol microinjection into the BST evokes pressor response due to vasopressin release into the circulation. Carbachol 130-139 arginine vasopressin Rattus norvegicus 199-210 20201386-4 2009 Menthol (0.1-1 mmol/l) per se virtually unaffected the basal tone, but inhibited in a dose-dependent manner KCl-, CCh- and Nor-evoked contractions of both parts of the vas deference by 30-50%. Carbachol 114-117 arginine vasopressin Rattus norvegicus 168-171 17306779-10 2007 In conclusion, results suggest that microinjection of CBH in the BST activates local M(2)-muscarinic receptor evoking pressor and bradycardiac responses, which are mediated by acute vasopressin release into circulation. Carbachol 54-57 arginine vasopressin Rattus norvegicus 182-193 15152572-0 2004 [Carbachol effect on kinetics of the alpha1-adrenergic contractile response of the rat vas deferens]. Carbachol 1-10 arginine vasopressin Rattus norvegicus 87-90 8761858-6 1996 In contrast, the increase in MAP evoked by 5.5 and 13.2 nmol CCh could be attenuated by prazosin, yohimbine, or D[(CH2)5Tyr(Me)]AVP (AVPX, a V 1-vasopressin receptor blocker), and completely blocked by the combination of prazosin and AVPX. Carbachol 61-64 arginine vasopressin Rattus norvegicus 145-156 8637618-14 1995 Angiotensin II and carbachol caused an approximate five-fold increase in plasma vasopressin levels compared to cerebrospinal fluid-injected rats, but angiotensin-(1-7) had no effect on vasopressin release. Carbachol 19-28 arginine vasopressin Rattus norvegicus 80-91 7936115-8 1994 In the presence of the vasopressin antagonist, d(CH2)5(Tyr(Et))DAVP, alone or in combination with phentolamine and propranolol, the pressor response to carbachol was substantially reduced, while the renal and superior mesenteric vasoconstrictor effects were completely abolished; the bradycardia was not significantly affected by this treatment. Carbachol 152-161 arginine vasopressin Rattus norvegicus 23-34 7936115-9 1994 These results indicate an important involvement of vasopressin in the cardiovascular responses to carbachol injected into the PVN of untreated animals. Carbachol 98-107 arginine vasopressin Rattus norvegicus 51-62 7936115-10 1994 Moreover, in the presence of the vasopressin antagonist the hindquarters vascular bed showed a vasodilatation following PVN injection of carbachol; this effect was reversed to a vasoconstriction following combined i.v. Carbachol 137-146 arginine vasopressin Rattus norvegicus 33-44