PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
17307332-4	2007	Similarly, PKC inhibition enhanced EGFR transactivation in human colonic epithelial T84 cells stimulated with carbachol, as well as in bombesin-stimulated Rat-1 fibroblasts stably transfected with the bombesin receptor.	Carbachol	110-119	protein kinase C, alpha	Rattus norvegicus	11-14	
20495491-3	2010	RESULTS: The results indicated that PKCalpha and epsilon agonists, thymelea toxin and carbachol, restored shock-induced decrease of vascular calcium sensitivity; PKCalpha antagonist, Go-6976 and PKCepsilon pseudosubstrate inhibition peptide, aggravated shock-induced calcium desensitization, whereas the agonists and antagonists of PKCdelta and zeta had no effects on shock-induced calcium desensitization.	Carbachol	86-95	protein kinase C, alpha	Rattus norvegicus	36-44	
20495491-3	2010	RESULTS: The results indicated that PKCalpha and epsilon agonists, thymelea toxin and carbachol, restored shock-induced decrease of vascular calcium sensitivity; PKCalpha antagonist, Go-6976 and PKCepsilon pseudosubstrate inhibition peptide, aggravated shock-induced calcium desensitization, whereas the agonists and antagonists of PKCdelta and zeta had no effects on shock-induced calcium desensitization.	Carbachol	86-95	protein kinase C, alpha	Rattus norvegicus	162-170	
19373133-6	2010	The results indicated that PKC-alpha and PKC-epsilon agonists thymelea toxin and carbachol seemed to increase the calcium sensitivity and MLC20 phosphorylation of superior mesenteric artery after hemorrhagic shock and antagonize the increase of MLCP activity in VSMC after hypoxia.	Carbachol	81-90	protein kinase C, alpha	Rattus norvegicus	27-36	
15217780-1	2004	PKC is known to be activated by pancreatic secretagogues such as CCK and carbachol and to participate along with calcium in amylase release.	Carbachol	73-82	protein kinase C, alpha	Rattus norvegicus	0-3	
15894015-3	2005	Carbachol (CCh) caused translocations of PKC-alpha, betaII, delta, and epsilon from the cytosol to the plasma membrane.	Carbachol	0-9	protein kinase C, alpha	Rattus norvegicus	41-50	
15894015-3	2005	Carbachol (CCh) caused translocations of PKC-alpha, betaII, delta, and epsilon from the cytosol to the plasma membrane.	Carbachol	11-14	protein kinase C, alpha	Rattus norvegicus	41-50	
15894015-5	2005	The CCh-stimulated insulin secretion was significantly suppressed by the generic PKC inhibitor chelerythrine.	Carbachol	4-7	protein kinase C, alpha	Rattus norvegicus	81-84	
15894015-7	2005	These results suggest that the novel PKC isoforms activated by CCh, i.e., PKC-delta and/or epsilon, participate in the stimulatory effect of CCh on insulin secretion.	Carbachol	63-66	protein kinase C, alpha	Rattus norvegicus	37-40	
15894015-7	2005	These results suggest that the novel PKC isoforms activated by CCh, i.e., PKC-delta and/or epsilon, participate in the stimulatory effect of CCh on insulin secretion.	Carbachol	141-144	protein kinase C, alpha	Rattus norvegicus	37-40	
9604867-7	1998	Thus the carbachol activation of PKC appeared also to be dissociated from the stimulation of insulin release.	Carbachol	9-18	protein kinase C, alpha	Rattus norvegicus	33-36	
12612139-9	2003	In conclusion, a reduced expression of PKCalpha and PLCbeta(1) may be involved in the decreased insulin secretion by islets from LP rats after stimulation with CCh and PMA.	Carbachol	160-163	protein kinase C, alpha	Rattus norvegicus	39-47	
9604867-8	1998	However, when the activation of several different PKC isozymes was studied, an atypical PKC isozyme, zeta, was found to be translocated by carbachol.	Carbachol	139-148	protein kinase C, alpha	Rattus norvegicus	50-53	
9604867-8	1998	However, when the activation of several different PKC isozymes was studied, an atypical PKC isozyme, zeta, was found to be translocated by carbachol.	Carbachol	139-148	protein kinase C, alpha	Rattus norvegicus	88-91	
9604867-9	1998	By Western blotting analysis, carbachol selectively translocated the conventional PKC isozymes alpha and beta (the activation of which is dependent on Ca2+ and DAG) from the cytosol to the membrane.	Carbachol	30-39	protein kinase C, alpha	Rattus norvegicus	82-85	
9604867-15	1998	The data indicate that carbachol-stimulated insulin release in RINm5F cells is mediated to a large degree by the activation of the atypical PKC isozyme zeta.	Carbachol	23-32	protein kinase C, alpha	Rattus norvegicus	140-143	
7524684-6	1994	Specific receptor antagonists could prevent, as well as reverse completely, the translocation of PKC isoforms caused by CCK-8 or carbachol.	Carbachol	129-138	protein kinase C, alpha	Rattus norvegicus	97-100	
7475951-6	1995	Biochemical assay of total PKC confirmed that cytosolic enzyme activity was significantly reduced by TPA and carbachol to 29% and 75% respectively of control levels.	Carbachol	109-118	protein kinase C, alpha	Rattus norvegicus	27-30	
8076696-1	1994	The purpose of this study was to determine the role of protein kinase C (PKC) isozymes in carbachol-induced protein secretion in the lacrimal gland.	Carbachol	90-99	protein kinase C, alpha	Rattus norvegicus	73-76