PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7840204-4 1995 The stimulatory effects of carbachol on goblet cell degranulation in isolated pancreatic ducts were blocked by atropine and enhanced by simultaneous exposure to VIP. Carbachol 27-36 VIP peptides Cavia porcellus 161-164 9490877-12 1998 Tissue incubation with carbachol or VIP significantly potentiated delta Isc induced by VIP and carbachol, respectively, indicating cross-potentiation. Carbachol 23-32 VIP peptides Cavia porcellus 87-90 9490877-12 1998 Tissue incubation with carbachol or VIP significantly potentiated delta Isc induced by VIP and carbachol, respectively, indicating cross-potentiation. Carbachol 95-104 VIP peptides Cavia porcellus 36-39 8762078-7 1996 VIP was a more potent relaxant in tissues that were contracted with carbachol than those contracted with an equi-effective depolarizing concentration of K+. Carbachol 68-77 VIP peptides Cavia porcellus 0-3 16324225-0 2005 Restoration by VIP of the carbachol-stimulated Cl- secretion in TTX-treated guinea pig distal colon. Carbachol 26-35 VIP peptides Cavia porcellus 15-18 16324225-5 2005 However, a serosal application, not mucosal, of VIP (10(-7) M) and 8-bromo-cAMP (10(-3) M) restored the Cch-stimulated, TTX-inhibited I(sc) by 113% and 75.8%, respectively. Carbachol 104-107 VIP peptides Cavia porcellus 48-51 15518913-1 2004 A novel VIP derivative, [R15, 20, 21, L17]-VIP-GRR (IK312532), relaxed potently the carbachol-induced contraction of guinea-pig isolated trachea with longer duration than that induced by VIP. Carbachol 84-93 VIP peptides Cavia porcellus 43-46 10683200-2 2000 VIP induced a concentration-dependent inhibition of carbachol-induced contraction in smooth muscle cells with a maximum at 10(-6) M. The relaxation by 10(-6) M VIP was inhibited for 79.1+/-5.8% (mean+/-s.e. Carbachol 52-61 VIP peptides Cavia porcellus 0-3 10683200-2 2000 VIP induced a concentration-dependent inhibition of carbachol-induced contraction in smooth muscle cells with a maximum at 10(-6) M. The relaxation by 10(-6) M VIP was inhibited for 79.1+/-5.8% (mean+/-s.e. Carbachol 52-61 VIP peptides Cavia porcellus 160-163 7557075-7 1995 ANP and VIP inhibited 1 mumol/L carbachol-induced contraction in a dose-dependent manner. Carbachol 32-41 VIP peptides Cavia porcellus 8-11 7535425-7 1994 VIP and galanin alone had no effect on cell length, but each caused a dose-dependent inhibition of carbachol-induced contraction and both had an EC50 of 3-7 nM. Carbachol 99-108 VIP peptides Cavia porcellus 0-3 7912276-8 1994 High extracellular potassium concentrations or carbachol evoked release of endogenous VIP. Carbachol 47-56 VIP peptides Cavia porcellus 86-89 3246807-5 1988 VIP (10(-6) M) inhibited spontaneous and carbachol (10(-8) M)-stimulated propulsive activities of the isolated segment in distal colon. Carbachol 41-50 VIP peptides Cavia porcellus 0-3 8368310-6 1993 [4Cl-D-Phe6,Leu17]VIP (3.3 mg/kg), an antagonist to VIP, reduced basal, VIP-stimulated, and carbachol-stimulated HCO3- secretion. Carbachol 92-101 VIP peptides Cavia porcellus 18-21 8368310-6 1993 [4Cl-D-Phe6,Leu17]VIP (3.3 mg/kg), an antagonist to VIP, reduced basal, VIP-stimulated, and carbachol-stimulated HCO3- secretion. Carbachol 92-101 VIP peptides Cavia porcellus 52-55 8368310-6 1993 [4Cl-D-Phe6,Leu17]VIP (3.3 mg/kg), an antagonist to VIP, reduced basal, VIP-stimulated, and carbachol-stimulated HCO3- secretion. Carbachol 92-101 VIP peptides Cavia porcellus 52-55 1437521-2 1992 Vasoactive intestinal polypeptide (VIP) produced a dose-dependent depolarisation (EC50 = 30 nM) and an increase in membrane conductance that could be potentiated by carbachol. Carbachol 165-174 VIP peptides Cavia porcellus 0-33 1437521-2 1992 Vasoactive intestinal polypeptide (VIP) produced a dose-dependent depolarisation (EC50 = 30 nM) and an increase in membrane conductance that could be potentiated by carbachol. Carbachol 165-174 VIP peptides Cavia porcellus 35-38 1347975-3 1992 However, they reversed vasoactive intestinal peptide (VIP)-induced inhibition (relaxation) of carbachol-stimulated contraction. Carbachol 94-103 VIP peptides Cavia porcellus 54-57 2551183-1 1989 When dispersed acini from guinea pig pancreas are first incubated with carbachol, the subsequent binding of 125I-vasoactive intestinal peptide (VIP) is inhibited during a second incubation. Carbachol 71-80 VIP peptides Cavia porcellus 108-142 2551183-1 1989 When dispersed acini from guinea pig pancreas are first incubated with carbachol, the subsequent binding of 125I-vasoactive intestinal peptide (VIP) is inhibited during a second incubation. Carbachol 71-80 VIP peptides Cavia porcellus 144-147 2551183-2 1989 This inhibitory action of carbachol on binding of 125I-VIP depends on time, temperature, and the concentration of carbachol in the first incubation and can be blocked by atropine. Carbachol 26-35 VIP peptides Cavia porcellus 55-58 2551183-2 1989 This inhibitory action of carbachol on binding of 125I-VIP depends on time, temperature, and the concentration of carbachol in the first incubation and can be blocked by atropine. Carbachol 114-123 VIP peptides Cavia porcellus 55-58 2551183-4 1989 Adding EGTA to the first incubation medium abolishes the effect of carbachol on binding of 125I-VIP. Carbachol 67-76 VIP peptides Cavia porcellus 96-99 2551183-5 1989 In control acini or acini first incubated with carbachol, approximately half of the bound 125I-VIP can be stripped by acetic acid. Carbachol 47-56 VIP peptides Cavia porcellus 95-98 2551183-10 1989 The dose-response curve for carbachol-induced inhibition of binding of 125I-VIP and that for occupation of low-affinity muscarinic cholinergic receptors by carbachol are similar. Carbachol 28-37 VIP peptides Cavia porcellus 76-79 6098141-6 1984 In carbachol-contracted tracheas with maximally effective concentrations present of adenosine (3 mM), adenine (3 mM) or VIP (23.3 microM), the non-adrenergic neurogenic inhibitory response remained intact. Carbachol 3-12 VIP peptides Cavia porcellus 120-123 6089131-5 1984 The secretory responses induced by carbachol (CCh) at any concentrations were not potentiated but inhibited by simultaneous stimulation of VIP. Carbachol 35-44 VIP peptides Cavia porcellus 139-142 6089131-5 1984 The secretory responses induced by carbachol (CCh) at any concentrations were not potentiated but inhibited by simultaneous stimulation of VIP. Carbachol 46-49 VIP peptides Cavia porcellus 139-142 6714311-1 1984 Vasoactive intestinal peptide (VIP) relaxed isolated guinea pig airways contracted with carbamylcholine and isolated pulmonary arteries contracted with prostaglandin F2 alpha. Carbachol 88-103 VIP peptides Cavia porcellus 0-29 6714311-1 1984 Vasoactive intestinal peptide (VIP) relaxed isolated guinea pig airways contracted with carbamylcholine and isolated pulmonary arteries contracted with prostaglandin F2 alpha. Carbachol 88-103 VIP peptides Cavia porcellus 31-34 6197124-1 1983 Propranolol-resistant neurogenic relaxation persisted in (carbachol-contracted) guinea-pig tracheae already relaxed by supramaximal concentrations of vasoactive intestinal polypeptide (VIP). Carbachol 58-67 VIP peptides Cavia porcellus 150-183 6197124-1 1983 Propranolol-resistant neurogenic relaxation persisted in (carbachol-contracted) guinea-pig tracheae already relaxed by supramaximal concentrations of vasoactive intestinal polypeptide (VIP). Carbachol 58-67 VIP peptides Cavia porcellus 185-188 6245588-2 1980 Each enterocyte possessed approximately 60,000 binding sites and binding of the tracer to these sites could be inhibited by VIP [concentration for half-maximal effect (Kd), 12 nM] and by secretin (Kd greater than 1 micro M), but not by glucagon, gastrin, cholecystokinin, calcitonin, bombesin, litorin, physalaemin, substance P, eledoisin, serotonin, carbamylcholine, or histamine. Carbachol 351-366 VIP peptides Cavia porcellus 124-127 6177536-0 1982 Carbachol potentiates the cyclic AMP-stimulating effect of VIP in cat submandibular gland. Carbachol 0-9 VIP peptides Cavia porcellus 59-62 6177536-4 1982 The addition of carbachol potentiated the cyclic AMP response to VIP in the submandibular acini while no such effect was observed in the pancreas. Carbachol 16-25 VIP peptides Cavia porcellus 65-68