PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2543582-3 1989 We found increased CRABP after daily application during 4 days of natural or synthetic retinoids (RA, acitretin, isotretinoin, Ro137410, retinol), that have either a high affinity to CRABP or can be transformed into RA. Acitretin 102-111 cellular retinoic acid binding protein 1 Homo sapiens 19-24 2547418-5 1989 Oral treatment with acitretin and Ro137410 led to a striking increase of epidermal CRABP (from 2.6 +/- 0.9 to 16.2 +/- 2.9, P less than 0.004 and from 2.5 +/- 1.2 to 21.5 +/- 3.4 pmol/mg protein, P less than 0.004, respectively), while isotretinoin failed to induce a comparable rise (3.2 +/- 1.6 before and 3.7 +/- 0.7 pmol/mg protein after treatment), although it displayed in all patients a striking sebostatic effect. Acitretin 20-29 cellular retinoic acid binding protein 1 Homo sapiens 83-88 28421560-18 1992 Acitretin binds competitively to CRABP, a protein present in high concentrations in psoriatic plaques, and induces a marked elevation of CRABP levels in normal epidermis. Acitretin 0-9 cellular retinoic acid binding protein 1 Homo sapiens 33-38 28421560-18 1992 Acitretin binds competitively to CRABP, a protein present in high concentrations in psoriatic plaques, and induces a marked elevation of CRABP levels in normal epidermis. Acitretin 0-9 cellular retinoic acid binding protein 1 Homo sapiens 137-142