PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
2531718-4	1989	Nevertheless, sulpiride-induced prolactin secretion was significantly lower after Alpha-hANP administration than after placebo pre-treatment (p values ranging between 0.01 and 0.001).	Sulpiride	14-23	prolactin	Homo sapiens	32-41	
3183301-4	1988	The serum prolactin levels of 51-100 ng/ml in 11 subjects may have been induced by drugs (sulpiride) or unknown factors.	Sulpiride	90-99	prolactin	Homo sapiens	10-19	
2830786-3	1988	Before glucocorticoid replacement therapy, both TRH and sulpiride administration resulted in PRL hyper-responsiveness.	Sulpiride	56-65	prolactin	Homo sapiens	93-96	
3346364-5	1988	Compared with the placebo group, which had the expected postpartum plasma PRL decline, the sulpiride-treated women maintained significantly elevated basal plasma PRL values up to the 90th postpartum day.	Sulpiride	91-100	prolactin	Homo sapiens	74-77	
3346364-5	1988	Compared with the placebo group, which had the expected postpartum plasma PRL decline, the sulpiride-treated women maintained significantly elevated basal plasma PRL values up to the 90th postpartum day.	Sulpiride	91-100	prolactin	Homo sapiens	162-165	
2830786-2	1988	Prolactin (PRL) secretory dynamics were evaluated by several stimulation (thyrotropin-releasing hormone [TRH], sulpiride) and suppression (L-dopa) tests.	Sulpiride	111-120	prolactin	Homo sapiens	0-9	
2830786-4	1988	The sulpiride-induced PRL increase was higher than that induced by TRH.	Sulpiride	4-13	prolactin	Homo sapiens	22-25	
2830786-6	1988	Following glucocorticoid replacement therapy, the elevated basal PRL level returned to normal, and PRL hyper-responsiveness to TRH or sulpiride also returned to normal.	Sulpiride	134-143	prolactin	Homo sapiens	99-102	
3096790-3	1986	Daily administration of sulpiride (150 mg orally) significantly elevated serum prolactin (PRL) levels in all six women.	Sulpiride	24-33	prolactin	Homo sapiens	79-88	
3620290-0	1987	Prolactin response to low dose sulpiride.	Sulpiride	31-40	prolactin	Homo sapiens	0-9	
3620290-1	1987	1 Prolactin levels in response to sulpiride were studied in healthy volunteers.	Sulpiride	34-43	prolactin	Homo sapiens	2-11	
3620290-5	1987	6 These results indicate that sulpiride retains its potent ability to produce prolactin release even at the low doses studied here.	Sulpiride	30-39	prolactin	Homo sapiens	78-87	
3108355-8	1987	In the first protocol, PRL showed a significant increase (peak values at 30 min) after SUL administration in both phases (phase A: 54.8 +/- 5.6 ng/ml, mean +/- SE vs 6.4 +/- 0.3, p less than 0.001.	Sulpiride	87-90	prolactin	Homo sapiens	23-26	
3108355-11	1987	Also in the second protocol, SUL alone induced a significant PRL increase (peak values at 30 min: 47.1 +/- 7.2 vs 4.2 +/- 0.5, p less than 0.005).	Sulpiride	29-32	prolactin	Homo sapiens	61-64	
3613693-2	1987	Sulpiride (200 mg) was used as a control drug; it raised PRL by almost 800%.	Sulpiride	0-9	prolactin	Homo sapiens	57-60	
3121569-4	1987	Similarly, sulpiride, a D-2 dopamine receptor blocker, induced an increase in serum prolactin, which appeared to be maximal at a dose of 25 mg (6,556.3 +/- 636.9 ng prolactin/420 min compared with 6,594.5 +/- 169.3 ng prolactin/420 min with 100 mg sulpiride; P less than .10).	Sulpiride	11-20	prolactin	Homo sapiens	84-93	
3121569-4	1987	Similarly, sulpiride, a D-2 dopamine receptor blocker, induced an increase in serum prolactin, which appeared to be maximal at a dose of 25 mg (6,556.3 +/- 636.9 ng prolactin/420 min compared with 6,594.5 +/- 169.3 ng prolactin/420 min with 100 mg sulpiride; P less than .10).	Sulpiride	11-20	prolactin	Homo sapiens	165-174	
3121569-4	1987	Similarly, sulpiride, a D-2 dopamine receptor blocker, induced an increase in serum prolactin, which appeared to be maximal at a dose of 25 mg (6,556.3 +/- 636.9 ng prolactin/420 min compared with 6,594.5 +/- 169.3 ng prolactin/420 min with 100 mg sulpiride; P less than .10).	Sulpiride	11-20	prolactin	Homo sapiens	165-174	
3121569-4	1987	Similarly, sulpiride, a D-2 dopamine receptor blocker, induced an increase in serum prolactin, which appeared to be maximal at a dose of 25 mg (6,556.3 +/- 636.9 ng prolactin/420 min compared with 6,594.5 +/- 169.3 ng prolactin/420 min with 100 mg sulpiride; P less than .10).	Sulpiride	248-257	prolactin	Homo sapiens	84-93	
3096790-3	1986	Daily administration of sulpiride (150 mg orally) significantly elevated serum prolactin (PRL) levels in all six women.	Sulpiride	24-33	prolactin	Homo sapiens	90-93	
6199950-0	1984	Time course for effects of sulpiride and chlorpromazine on monoamine metabolite and prolactin levels in cerebrospinal fluid from schizophrenic patients.	Sulpiride	27-36	prolactin	Homo sapiens	84-93	
3785645-0	1986	Effect of sulpiride on plasma prolactin in healthy volunteers and depressed patients.	Sulpiride	10-19	prolactin	Homo sapiens	30-39	
3935458-11	1985	reversed the blunted response of PRL after sulpiride, 25 mg, in presence of naloxone.	Sulpiride	43-52	prolactin	Homo sapiens	33-36	
3935458-13	1985	inactive per se on basal PRL levels, is able to blunt significantly sulpiride-induced hyperprolactinaemia.	Sulpiride	68-77	prolactin	Homo sapiens	25-28	
4031381-9	1985	0.2 mg terguride bid given for 15 days to 7 healthy volunteers significantly reduced both basal and sulpiride (25 mg im)-stimulated PRL levels.	Sulpiride	100-109	prolactin	Homo sapiens	132-135	
4001434-1	1985	The relationship between erectile dysfunction and sulpiride stimulatory effect on prolactin secretion was studied in 13 married male psychiatric outpatients.	Sulpiride	50-59	prolactin	Homo sapiens	82-91	
4089188-0	1985	Effect of normal aging on the prolactin response to graded doses of sulpiride and to arginine.	Sulpiride	68-77	prolactin	Homo sapiens	30-39	
6440785-3	1984	Mean (+/- SE) plasma levels of PRL on day 7 in the sulpiride treated cycle were significantly higher than those in the control cycle (118 +/- 24 ng/ml vs. 14 +/- 4 ng/ml, p less than 0.001).	Sulpiride	51-60	prolactin	Homo sapiens	31-34	
6090494-3	1984	Long term administration of sulpiride to normal women increased both serum PRL and DHEA-S, whereas acute elevation of PRL after a single iv dose of domperidone had no influence on the serum DHEA-S levels.	Sulpiride	28-37	prolactin	Homo sapiens	75-78	
6394371-7	1984	Moreover another antagonist, sulpiride also increased PRL but contrary tended to decrease PAC.	Sulpiride	29-38	prolactin	Homo sapiens	54-57	
3122863-1	1986	Plasma prolactin and GH responses following TRH, sulpiride, L-dopa, and bromocriptine administration.	Sulpiride	49-58	prolactin	Homo sapiens	7-16	
2943108-9	1986	(Normal values of prolactin were on the average achieved on the 4th day after sulpiride discontinuation).	Sulpiride	78-87	prolactin	Homo sapiens	18-27	
3888233-0	1985	Prolactin response to sulpiride in non insulin dependent diabetes mellitus.	Sulpiride	22-31	prolactin	Homo sapiens	0-9	
3888233-3	1985	Prolactin response to sulpiride was significantly higher in diabetics than in controls (at 20 min., p less than 0.01; at 30 and 60 min., p less than 0.005; at 90 min., p less than 0.01; at 120 min., p less than 0.05).	Sulpiride	22-31	prolactin	Homo sapiens	0-9	
3888233-5	1985	Prolactin response to sulpiride was the same in diabetics with and in those without retinal changes.	Sulpiride	22-31	prolactin	Homo sapiens	0-9	
4040306-5	1985	The LH and FSH responses to LHRH were similar to those of XXY controls, and the variation of prolactin levels after sulpiride stimulus was in the normal range.	Sulpiride	116-125	prolactin	Homo sapiens	93-102	
3988149-4	1985	Sulpiride resulted in a much greater PRL response.	Sulpiride	0-9	prolactin	Homo sapiens	37-40	
6528338-8	1984	Plasma PRL response to sulpiride also became exaggerated during the treatment.	Sulpiride	23-32	prolactin	Homo sapiens	7-10	
6421041-7	1984	When perifused simultaneously with dopamine, sulpiride (D2-selective dopamine receptor blocker, 5 X 10(-7) M) blocked the inhibitory effect of dopamine on Prl release in 3 of the 4 dopamine-sensitive prolactinomas.	Sulpiride	45-54	prolactin	Homo sapiens	155-158	
6439566-0	1984	Possible mechanism of prolactin unresponsiveness to repeated sulpiride administration in man.	Sulpiride	61-70	prolactin	Homo sapiens	22-31	
6146579-0	1984	Prolactin response to sulpiride in ovulatory women (a clue for the screening of hyperprolactinemic states).	Sulpiride	22-31	prolactin	Homo sapiens	0-9	
6146579-2	1984	The dynamics of prolactin secretion was investigated in 30 ovulatory females subjected to sulpiride stimulation.	Sulpiride	90-99	prolactin	Homo sapiens	16-25	
6146579-5	1984	We conclude that basal prolactin levels and the 30-min value after sulpiride administration seem to be sufficient and valid representative estimations in the screening of abnormal prolactin secretion states.	Sulpiride	67-76	prolactin	Homo sapiens	180-189	
6199950-7	1984	There were significantly higher PRL levels in sulpiride- than in chlorpromazine-treated patients.	Sulpiride	46-55	prolactin	Homo sapiens	32-35	
6199950-9	1984	The HVA/PRL ratio in CSF was significantly reduced in the sulpiride but not in the chlorpromazine group.	Sulpiride	58-67	prolactin	Homo sapiens	8-11	
6199950-15	1984	The different effects of the drugs on PRL, 5-HIAA and MOPEG levels indicate that sulpiride has a more specific effect than chlorpromazine on dopaminergic mechanisms.	Sulpiride	81-90	prolactin	Homo sapiens	38-41	
6762263-8	1982	Plasma PRL levels resulted significantly higher in sulpiride treated groups than in placebo group.	Sulpiride	51-60	prolactin	Homo sapiens	7-10	
6361642-4	1984	The concentration of prolactin in maternal serum was higher (P less than .001) during sulpiride than placebo treatment at one week (380 +/- 43 ng/ml vs 23 +/- 7 ng/ml, mean +/- SE) and two weeks of treatment (381 +/- 38 ng/ml vs 34 +/- 10 ng/ml).	Sulpiride	86-95	prolactin	Homo sapiens	21-30	
6403571-5	1983	Conversely, an iv bolus of sulpiride (25 mg), a dopaminergic antagonist, given to four subjects after 240 min, brought about a marked increase in serum PRL values above the plateau level.	Sulpiride	27-36	prolactin	Homo sapiens	152-155	
6680345-0	1983	[Effect of sulpiride on the secretion of prolactin and somatotropic hormone in premenopausal women affected by fibrocystic mastopathy].	Sulpiride	11-20	prolactin	Homo sapiens	41-50	
6851194-5	1983	Conversely, sulpiride and domperidone strikingly stimulated PRL secretion in normoprolactinaemic and post-partum women, but only slightly enhanced base-line PRL levels in women with prolactinomas.	Sulpiride	12-21	prolactin	Homo sapiens	60-63	
6628512-1	1983	The prolactin (PRL) response to repeated injections of sulpiride, a dopamine antagonist, was evaluated in 18 healthy young men.	Sulpiride	55-64	prolactin	Homo sapiens	4-13	
6628512-1	1983	The prolactin (PRL) response to repeated injections of sulpiride, a dopamine antagonist, was evaluated in 18 healthy young men.	Sulpiride	55-64	prolactin	Homo sapiens	15-18	
6628512-4	1983	The second injection up to 24 h had no effect on serum PRL, but when two sulpiride injections were given at a 48 h-interval, both caused a sharp increase in PRL.	Sulpiride	73-82	prolactin	Homo sapiens	157-160	
6628512-5	1983	To conclude, PRL cells in man, after a sulpiride injection, may therefore be unresponsive to a second sulpiride injection for more than 24 h.	Sulpiride	39-48	prolactin	Homo sapiens	13-16	
6642291-0	1983	Prolactin response to the dopamine antagonists sulpiride and domperidone.	Sulpiride	47-56	prolactin	Homo sapiens	0-9	
6812343-4	1982	Serum Prl levels after sulpiride were higher in the patients than in the controls (P less than 0.01).	Sulpiride	23-32	prolactin	Homo sapiens	6-9	
6812343-7	1982	The markedly enhanced Prl response to sulpiride in our patients with galactorrhoea could be due to a functional disorder of the hypothalamic-pituitary axis or to a lactotrope hyperplasia.	Sulpiride	38-47	prolactin	Homo sapiens	22-25	
7102768-5	1982	Determinations of daily serum levels of prolactin in 20 primiparous women revealed significantly higher concentrations in the sulpiride group.	Sulpiride	126-135	prolactin	Homo sapiens	40-49	
7171172-0	1982	Possible involvement of prolactin in sulpiride-induced changes in nigral and striatal GAD activity.	Sulpiride	37-46	prolactin	Homo sapiens	24-33	
7094872-3	1982	Very significant changes in GAD activity were only observed with sulpiride and nomifensine, two atypical antidepressants that selectively influence dopaminergic transmission and, in turn, prolactin secretion.	Sulpiride	65-74	prolactin	Homo sapiens	188-197	
7152714-0	1982	Effects of sulpiride treatment on plasma prolactin and steroid hormones in early human pregnancy.	Sulpiride	11-20	prolactin	Homo sapiens	41-50	
6139285-6	1983	Administration of the same dose of domperidone or sulpiride (5 mg/kg i.p., 21 days), compounds which penetrate poorly into brain, also elevated plasma prolactin levels, but failed to alter cerebral dopamine function.	Sulpiride	50-59	prolactin	Homo sapiens	151-160	
6226542-1	1983	In order to investigate the relationship between the increment of plasma prolactin (PRL) levels and the change of plasma levels of PRL, DHEA-S, cortisol, aldosterone and 17 alpha OH delta 5-P were quantified by respective RIA in patients treated with TRH parenterally or with sulpiride orally.	Sulpiride	276-285	prolactin	Homo sapiens	73-82	
6226542-3	1983	Sulpiride given orally for 12 consecutive days in the luteal phase of the menstrual cycle caused a significant increase in the plasma PRL level.	Sulpiride	0-9	prolactin	Homo sapiens	134-137	
6414103-0	1983	Persistence of impaired PRL responses to sulpiride in patients with PRL secreting pituitary adenomas after successful hypophysectomy.	Sulpiride	41-50	prolactin	Homo sapiens	24-27	
6414103-0	1983	Persistence of impaired PRL responses to sulpiride in patients with PRL secreting pituitary adenomas after successful hypophysectomy.	Sulpiride	41-50	prolactin	Homo sapiens	68-71	
6414103-5	1983	On the other hand, the PRL responses to sulpiride in both Groups I and II improved markedly after the hypophysectomy, but the absolute response in operated Group I patients was still lower than that in normal subjects.	Sulpiride	40-49	prolactin	Homo sapiens	23-26	
6414103-7	1983	It is concluded 1) that even in hypophysectomized normoprolactinemic patients the circulating PRL may originate mainly from the residual tumor cells, and 2) that the sulpiride test is useful to detect the abnormalities of hypothalamo-pituitary axis in operated patients with PRL-secreting adenomas, whereas TRH, arginine, and L-dopa tests are less useful for such purposes.	Sulpiride	166-175	prolactin	Homo sapiens	94-97	
6414103-7	1983	It is concluded 1) that even in hypophysectomized normoprolactinemic patients the circulating PRL may originate mainly from the residual tumor cells, and 2) that the sulpiride test is useful to detect the abnormalities of hypothalamo-pituitary axis in operated patients with PRL-secreting adenomas, whereas TRH, arginine, and L-dopa tests are less useful for such purposes.	Sulpiride	166-175	prolactin	Homo sapiens	275-278	
6807435-4	1982	In the sulpiride-treatment group the mean maternal serum prolactin concentration rose from 49.0 +/- SE 3.6 micrograms/l to a maximum of 402.1 +/0 43.2 micrograms/l at two weeks; in the placebo-treated group, however, the concentration fell during the trial (from 84.7 +/- 24.0 micrograms/l to 47.8 +/- 8.6 micrograms/l).	Sulpiride	7-16	prolactin	Homo sapiens	57-66	
6789593-0	1981	Dynamic evaluation of prolactin secretion with sulpiride and thyrotrophin releasing hormone in amenorrhoeic and normally menstruating women.	Sulpiride	47-56	prolactin	Homo sapiens	22-31	
6805007-0	1982	Prolactin response following intravenous and oral sulpiride in healthy human subjects in relation to sulpiride concentrations.	Sulpiride	50-59	prolactin	Homo sapiens	0-9	
6805007-0	1982	Prolactin response following intravenous and oral sulpiride in healthy human subjects in relation to sulpiride concentrations.	Sulpiride	101-110	prolactin	Homo sapiens	0-9	
6805007-2	1982	Serum concentrations of sulpiride and prolactin were followed for 36 h. Both routes of drug administration resulted in a pronounced and sustained increase in serum prolactin concentration.	Sulpiride	24-33	prolactin	Homo sapiens	164-173	
6805007-6	1982	The sustained prolactin elevation may be due to high affinity and strong binding of the compound to the regulating receptors or the formation of an active sulpiride metabolite.	Sulpiride	155-164	prolactin	Homo sapiens	14-23	
6805007-7	1982	Prolactin and sulpiride concentrations were significantly correlated during the initial phase after intravenous sulpiride.	Sulpiride	112-121	prolactin	Homo sapiens	0-9	
6805007-8	1982	Following intravenous and oral sulpiride the area under the concentration-time curve (AUC) for prolactin was similar despite a considerable difference in the sulpiride concentration.	Sulpiride	31-40	prolactin	Homo sapiens	95-104	
7327523-0	1981	Prolactin responsiveness to repeated decremental doses of sulpiride.	Sulpiride	58-67	prolactin	Homo sapiens	0-9	
7327523-1	1981	The variation in the prolactin response to sulpiride was studied in six normal men by repeating the same dose of the drug (50 mg) after 24 hours and on three subsequent occasions, repeating this 2 day test at an interval of 6 days with progressively halved doses of sulpiride.	Sulpiride	43-52	prolactin	Homo sapiens	21-30	
7327523-5	1981	The delta PRL increment on the second day was inversely proportional to the dose of sulpiride; the differences in delta PRL between periods 1 and 3 and periods 1 and 4 being highly significant (P less than 0.001).	Sulpiride	84-93	prolactin	Homo sapiens	10-13	
7327523-5	1981	The delta PRL increment on the second day was inversely proportional to the dose of sulpiride; the differences in delta PRL between periods 1 and 3 and periods 1 and 4 being highly significant (P less than 0.001).	Sulpiride	84-93	prolactin	Homo sapiens	120-123	
7327523-6	1981	This study suggests that a much lower dose of sulpiride than that normally used is adequate to stimulate PRL secretion and that care must be taken in the timing of repeat testing.	Sulpiride	46-55	prolactin	Homo sapiens	105-108	
6788792-0	1981	Prolactin response to sulpiride in hypogonadotropic, normogonadotropic, and hypergonadotropic primary amenorrhea.	Sulpiride	22-31	prolactin	Homo sapiens	0-9	
7211478-0	1980	Sulpiride stimulation of prolactin secretion in adolescents with gynecomastia: relation to the circulating levels of estradiol.	Sulpiride	0-9	prolactin	Homo sapiens	25-34	
6785431-0	1981	Serum prolactin concentrations in mangabey (Cercocebus atys lunulatus) and patas (Erythrocebus patas) monkeys in response to stress, ketamine, TRH, sulpiride and levodopa.	Sulpiride	148-157	prolactin	Homo sapiens	6-15	
6785431-11	1981	The variations in serum prolactin levels observed in these monkeys under the influence of stress, TRH, sulpiride and levodopa are similar to those observed in man to the same stimuli, although the experimental conditions were quite different.	Sulpiride	103-112	prolactin	Homo sapiens	24-33	
7435113-0	1980	Effect of sulpiride on plasma prolactin levels in women with puerperal or pathological hyperprolactinaemia.	Sulpiride	10-19	prolactin	Homo sapiens	30-39	
7435113-1	1980	The effect of 100 mg im sulpiride on plasma Prl levels was studied in 10 normal females, 21 patients with galactorrhoea and normal plasma Prl, 10 women with puerperal hyperprolactinaemia and 27 patients with amenorrhoea-galactorrhoea and high plasma Prl levels.	Sulpiride	24-33	prolactin	Homo sapiens	44-47	
7435113-2	1980	The response to sulpiride in patients with galactorrhoea but normal PRL was slightly higher (P < 0.05) than that observed in normal women, but only if expressed in per cent.	Sulpiride	16-25	prolactin	Homo sapiens	68-71	
7435113-6	1980	In the last 3 patients with pathological hyperprolactinaemia in whom a consistent Prl increase after sulpiride was observed, hyperprolactinaemia was probably not of tumourous origin.	Sulpiride	101-110	prolactin	Homo sapiens	82-85	
7435113-7	1980	On the basis of these results, the sulpiride test appears promising for discriminating between organic and "functional" cases of enhanced Prl secretion.	Sulpiride	35-44	prolactin	Homo sapiens	138-141	
6792868-2	1980	PRL-response to 200 micrograms of TRH was assessed in 41 cases, and PRL-response to sulpiride in 38 cases.	Sulpiride	84-93	prolactin	Homo sapiens	68-71	
6792868-10	1980	PRL-response to sulpiride doesn"t differ from that of normal males in the 3 categories of SD.	Sulpiride	16-25	prolactin	Homo sapiens	0-3	
6792868-11	1980	Research of linear correlations between scores of anxiety and depression and PRL maximal increments after TRH and sulpiride in EP and ANEJ is negative.	Sulpiride	114-123	prolactin	Homo sapiens	77-80	
6254696-1	1980	Sulpiride induces an increase in plasma prolactin and a simultaneous increase of aldosterone release in man.	Sulpiride	0-9	prolactin	Homo sapiens	40-49	
7380989-0	1980	Sulpiride treatment during early human pregnancy: effect on the levels of prolactin, six steroids, and placental lactogen.	Sulpiride	0-9	prolactin	Homo sapiens	74-83	
7380989-3	1980	Sulpiride treatment induced significant (P less than 0.001) elevations of plasma PRL at 1 week [84.1 +/- 4.9 vs. 23.7 +/- 2.8 ng/ml (mean +/- SE)] and 2 weeks (83.0 +/- 4.1 vs. 31.9 +/- 4.1 ng/ml).	Sulpiride	0-9	prolactin	Homo sapiens	81-84	
7386120-0	1980	Potentiation of sulpiride-induced prolactin secretion by sodium deprivation in man.	Sulpiride	16-25	prolactin	Homo sapiens	34-43	
6785978-6	1980	Higher than normal basal prolactin levels in some of the acromegalic patients and abnormal prolactin responses following sulpiride and TRH loading in most of the patients with acromegaly are attributed to deranged hypothalamo-hypophyseal regulation.	Sulpiride	121-130	prolactin	Homo sapiens	91-100	
6785978-3	1980	After sulpiride loading, maximum changes in prolactin level were significantly smaller in acromegalic patients, irrespective of the basal prolactin concentration.	Sulpiride	6-15	prolactin	Homo sapiens	44-53	
15107193-6	2004	Sulpiride caused an increase in prolactin (643 U/ml) [confidence interval (CI) 549-737).	Sulpiride	0-9	prolactin	Homo sapiens	32-41	
474034-0	1979	Study on the reproducibility of human prolactin response to sulpiride, benserazide, insulin hypoglycaemia and arginine infusion.	Sulpiride	60-69	prolactin	Homo sapiens	38-47	
474034-3	1979	In contrast to this, insulin hypoglycaemia yielded significantly lower PRL release, while the PRL response to the second sulpiride test was significantly higher than to the first one.	Sulpiride	121-130	prolactin	Homo sapiens	94-97	
474034-4	1979	When an interval of 10 days was left between two consecutive sulpiride tests, an identical PRL release was observed.	Sulpiride	61-70	prolactin	Homo sapiens	91-94	
474034-6	1979	Finally, sulpiride probably enhances both PRL release and synthesis thus making greater amounts of PRL available to a subsequent stimulus.	Sulpiride	9-18	prolactin	Homo sapiens	42-45	
474034-6	1979	Finally, sulpiride probably enhances both PRL release and synthesis thus making greater amounts of PRL available to a subsequent stimulus.	Sulpiride	9-18	prolactin	Homo sapiens	99-102	
288372-6	1979	This was suggested by the inhibitory effect of pretreatment with the dopamine antagonist spiroperidol or with sulpiride on the prolactin-lowering effect of lisuride.	Sulpiride	110-119	prolactin	Homo sapiens	127-136	
680182-0	1978	Release of prolactin during pregnancy: effect of sulpiride.	Sulpiride	49-58	prolactin	Homo sapiens	11-20	
680182-1	1978	The aim of this trial was to study the prolactin-releasing capacity of the pituitary during pregnancy by means of an acute stimulation with sulpiride.	Sulpiride	140-149	prolactin	Homo sapiens	39-48	
680182-8	1978	The prolactin-releasing capacity of the pituitary, as judged by the response to sulpiride, seems to be maintained during pregnancy.	Sulpiride	80-89	prolactin	Homo sapiens	4-13	
639330-5	1978	After sulpiride a 800-4200% increment of prolactin over control values was noted in the females and 1200-3500% increment in the males.	Sulpiride	6-15	prolactin	Homo sapiens	41-50	
639331-5	1978	After sulpiride a marked increase (3--10 times over control values) in PRL was noted in all normal and short children without pituitary disease.	Sulpiride	6-15	prolactin	Homo sapiens	71-74	
415471-4	1978	Two hundred microgram lisuride also decreased the high serum prolactin levels produced by im injection of 50 mg sulpiride, and conversely, sulpiride injection abolished the prolactin lowering effect of lisuride.	Sulpiride	112-121	prolactin	Homo sapiens	61-70	
415471-4	1978	Two hundred microgram lisuride also decreased the high serum prolactin levels produced by im injection of 50 mg sulpiride, and conversely, sulpiride injection abolished the prolactin lowering effect of lisuride.	Sulpiride	139-148	prolactin	Homo sapiens	173-182	
580204-0	1978	Serum prolactin levels after a single and subchronic oral administration of chlorpromazine and sulpiride.	Sulpiride	95-104	prolactin	Homo sapiens	6-15	
580204-2	1978	The effect of a single antianxiety dose of chlorpromazine (100 mg) and sulpiride (200 mg) on serum prolactin and gonadotrophins was studied in 6 healthy women in a cross-over study.	Sulpiride	71-80	prolactin	Homo sapiens	99-108	
580204-7	1978	In acute study sulpiride caused a fivefold increase in serum prolactin at 1 h. Chlorpromazine induced a slower and smaller increase.	Sulpiride	15-24	prolactin	Homo sapiens	61-70	
578618-0	1977	Stimulating action of sulpiride and pimozide on prolactin release.	Sulpiride	22-31	prolactin	Homo sapiens	48-57	
578618-2	1977	In order to evaluate the mechanism of action of metergoline, an antiserotonin agent, the effect of pre-treatment with metergoline on prolactin (PRL) release induced by sulpiride was compared to that obtained after bromocriptine administration in normal subjects.	Sulpiride	168-177	prolactin	Homo sapiens	133-142	
578618-2	1977	In order to evaluate the mechanism of action of metergoline, an antiserotonin agent, the effect of pre-treatment with metergoline on prolactin (PRL) release induced by sulpiride was compared to that obtained after bromocriptine administration in normal subjects.	Sulpiride	168-177	prolactin	Homo sapiens	144-147	
923106-2	1977	The prolactin lowering effect of this drug was abolished by sulpiride.	Sulpiride	60-69	prolactin	Homo sapiens	4-13	
406134-0	1977	Effect of sulpiride on serum growth hormone and prolactin concentrations following L-DOPA administration in man.	Sulpiride	10-19	prolactin	Homo sapiens	48-57	
406134-1	1977	The effect of chronic administration of sulpiride on serum human growth hormone (hGH), prolactin and thyroid stimulating hormone (TSH) was examined in 6 normal subjects.	Sulpiride	40-49	prolactin	Homo sapiens	87-96	
406134-4	1977	Sulpiride raised serum prolactin levels in all subjects examined.	Sulpiride	0-9	prolactin	Homo sapiens	23-32	
406134-6	1977	Sulpiride treatment appeared to antagonize partially the inhibitory effect of L-dopa on prolactin release.	Sulpiride	0-9	prolactin	Homo sapiens	88-97	
406134-7	1977	Following thyrotropin-releasing hormone (TRH) injection, the percent increment in prolactin levels from the baseline in sulpiride-treated subjects was less than in controls without sulpiride.	Sulpiride	120-129	prolactin	Homo sapiens	82-91	
406134-9	1977	These observations suggest that sulpiride suppresses L-dopa-induced hGH release and stimulates prolactin release, presumably by acting against the dopaminergic mechanism either on the hypothalamus or on the pituitary.	Sulpiride	32-41	prolactin	Homo sapiens	95-104	
406134-10	1977	The decreased prolactin response to TRH after sulpiride treatment may indicate a diminished reserve capacity in pituitary prolactin release.	Sulpiride	46-55	prolactin	Homo sapiens	14-23	
406134-10	1977	The decreased prolactin response to TRH after sulpiride treatment may indicate a diminished reserve capacity in pituitary prolactin release.	Sulpiride	46-55	prolactin	Homo sapiens	122-131	
856708-3	1977	Sulpiride, a benzamide derivative with neuroleptic and thymoleptic properties, is known to act at the hypothalamic level and in particular, to inhibit releasing factors responsible for follicle-stimulating hormone and prolactin secretion.	Sulpiride	0-9	prolactin	Homo sapiens	218-227	
977731-2	1976	A group of 6 normal men was treated for 4 consecutive days, on separate periods, with Sulpiride which is known to raise plasma prolactin (PRL) concentration.	Sulpiride	86-95	prolactin	Homo sapiens	127-136	
977731-2	1976	A group of 6 normal men was treated for 4 consecutive days, on separate periods, with Sulpiride which is known to raise plasma prolactin (PRL) concentration.	Sulpiride	86-95	prolactin	Homo sapiens	138-141	
1249187-0	1976	Effect of sulpiride on serum prolactin levels in humans.	Sulpiride	10-19	prolactin	Homo sapiens	29-38	
1249187-6	1976	Sulpiride induced in all subjects a quick and marked increment of serum prolactin levels with peak values at 30 minutes.	Sulpiride	0-9	prolactin	Homo sapiens	72-81	
813995-0	1975	Stimulation of human prolactin secretion by sulpiride.	Sulpiride	44-53	prolactin	Homo sapiens	21-30	
813995-1	1975	Intramuscular injection of 100 mg of sulpiride significantly raised plasma human prolactin (hPRL) levels in all of 7 normal subjects examined.	Sulpiride	37-46	prolactin	Homo sapiens	81-90	
813995-1	1975	Intramuscular injection of 100 mg of sulpiride significantly raised plasma human prolactin (hPRL) levels in all of 7 normal subjects examined.	Sulpiride	37-46	prolactin	Homo sapiens	92-96	
813995-3	1975	Daily administration of sulpiride (50 mg tid po) raised plasma hPRL levels in all 7 patients with peptic ulcer, with peak values obtained within 2 weeks.	Sulpiride	24-33	prolactin	Homo sapiens	63-67	
813995-5	1975	It is concluded that sulpiride stimulates hPRL secretion in man.	Sulpiride	21-30	prolactin	Homo sapiens	42-46	
467503-1	1979	Sulpiride, which differs from classical neuroleptics by not producing major extrapyramidal side effects, is a potent antiemetic agent and stimulates prolactin secretion in both laboratory animals and man.	Sulpiride	0-9	prolactin	Homo sapiens	149-158	
429499-1	1979	The effect of oral administration of sulpiride on PRL secretion and initiation of puerperal lactation was studied in 130 randomly selected primiparous nursing mothers.	Sulpiride	37-46	prolactin	Homo sapiens	50-53	
429499-5	1979	Every other day determinations of serum PRL levels revealed significantly higher concentrations in the sulpiride group than in the control group.	Sulpiride	103-112	prolactin	Homo sapiens	40-43	
429499-6	1979	A single oral dose of 50 mg sulpiride raised serum PRL levels for 12 h, with a peak level at 2 h after dosing in 7 women on the second postpartum day.	Sulpiride	28-37	prolactin	Homo sapiens	51-54	
429499-7	1979	These data suggest that sulpiride given orally promotes the initiation of lactation in puerperal women by stimulating PRL secretion.	Sulpiride	24-33	prolactin	Homo sapiens	118-121	
503288-0	1979	Restoration of the prolactin response to sulpiride by metergoline administration in hyperprolactinemic patients.	Sulpiride	41-50	prolactin	Homo sapiens	19-28	
709890-5	1978	Sulpiride prevented the inhibitory effect on PRL levels of 500 mg levodopa, administered orally simultaneously; levodopa administered 2 hours prior to sulpiride failed to counteract the PRL-stimulatory effect of sulpiride.	Sulpiride	0-9	prolactin	Homo sapiens	45-48	
580204-8	1978	Prolactin concentrations remained raised for at least 6 h. The initial raised prolactin concentration induced by sulpiride was associated with antidiuresis.	Sulpiride	113-122	prolactin	Homo sapiens	0-9	
580204-8	1978	Prolactin concentrations remained raised for at least 6 h. The initial raised prolactin concentration induced by sulpiride was associated with antidiuresis.	Sulpiride	113-122	prolactin	Homo sapiens	78-87	
580204-11	1978	It is concluded that in doses useful in the treatment of neurotic patients sulpiride causes a greater increase in serum prolactin levels than does chlorpromazine.	Sulpiride	75-84	prolactin	Homo sapiens	120-129	
738536-1	1978	Serum prolactin levels were determined following stimulation by sulpiride in 20 patients with nonalcoholic liver cirrhosis and 10 normal controls.	Sulpiride	64-73	prolactin	Homo sapiens	6-15	
738536-3	1978	Only 5 cirrhotics, all with ascites, showed a lower prolactin response after sulpiride stimulation.	Sulpiride	77-86	prolactin	Homo sapiens	52-61	
21571-0	1977	An evaluation of a unique new antipsychotic agent, sulpiride: effects on serum prolactin and growth hormone levels.	Sulpiride	51-60	prolactin	Homo sapiens	79-88	
410826-0	1977	Failure of dopamine infusion to suppress the plasma prolactin response to sulpiride in normal and hyperprolactinemic subjects.	Sulpiride	74-83	prolactin	Homo sapiens	52-61	
410826-3	1977	In four hyperprolactinemic women showing an impaired PRL response to sulpiride, dopamine infusion was effective both in lowering PRL circulating levels and in restoring an evident response to sulpiride.	Sulpiride	69-78	prolactin	Homo sapiens	53-56	
578053-0	1977	The stimulation of prolactin secretion by sulpiride in "adolescent gynaecomastia".	Sulpiride	42-51	prolactin	Homo sapiens	19-28	
874063-1	1977	Pasma prolactin response to the acute injection of sulpiride (1.5 mg/k BW im) was measured at 0800-0900h in 4 girls with idiopathic precocious puberty before and after 6 to 11 months of continuous therapy with 50 mg daily of cyproterone acetate (CA) orally administered.	Sulpiride	51-60	prolactin	Homo sapiens	6-15	
1243732-0	1975	[Effect of sulpiride and 2Br-alfa ergocryptine on the neuroendocrine control of hPRL incretion (author"s transl)].	Sulpiride	11-20	prolactin	Homo sapiens	80-84	
1243732-2	1975	The incretion of hPRL after infusion of SULPIRIDE (100 mg) by e.v.	Sulpiride	40-49	prolactin	Homo sapiens	17-21	
25610268-4	2013	We report a case of a 43-year-old woman with an extremely high prolactin level in medication-induced hyperprolactinemia caused by a combination of an antipsychotic (sulpirid) and an antidepressant (paroxetine).	Sulpiride	165-173	prolactin	Homo sapiens	63-72	
22472310-2	2012	Higher levels of prolactin result from longer exposure to higher doses, especially with older antipsychotics or with risperidone, sulpiride or amisulpride.	Sulpiride	130-139	prolactin	Homo sapiens	17-26	
11846864-7	2002	From the marked increase in PRL level and the slight decrease in T/E2 ratio observed during sulpiride therapy, it is proposed that sulpiride may induce gynecomastia by inhibiting hypothalamic-pituitary function directly, and/or indirectly through hyperPRLemia.	Sulpiride	131-140	prolactin	Homo sapiens	28-31	
12568792-4	2003	We carried out a biological validation of the prolactin assay by administering three different doses each of sulpiride and cabergoline to adult male meerkats.	Sulpiride	109-118	prolactin	Homo sapiens	46-55	
12568792-5	2003	Increasing doses of sulpiride and cabergoline caused substantial increases and decreases, respectively, in the plasma prolactin of the study animals as expected.	Sulpiride	20-29	prolactin	Homo sapiens	118-127	
12574225-6	2003	LIF (5 nM) treatment reduced PRL secretion in primary human prolactinoma cultures by up to 42% (P < 0.0005), an effect that was surprisingly blocked by sulpiride, a D2-like dopamine receptor antagonist.	Sulpiride	155-164	prolactin	Homo sapiens	29-32	
12950692-1	2003	The aim of this study was to compare the effects of treatment with repeated injections of sulpiride (a dopamine D2 antagonist) on prolactin secretion and induced lactation in ovariectomized and intact adult mares and to verify if this induction was possible at the beginning and at the end of the birth season.	Sulpiride	90-99	prolactin	Homo sapiens	130-139	
12950692-10	2003	Prolactin increase after sulpiride treatment was not so great in the ovariectomized-treated mares as in the intact-treated mares.	Sulpiride	25-34	prolactin	Homo sapiens	0-9	
20681131-7	2000	Sulpiride administration increased plasma prolactin concentrations at all times of the year and was most pronounced in cyclic mares, whereas naloxone administration did not affect prolactin secretion.	Sulpiride	0-9	prolactin	Homo sapiens	42-51	
11998830-0	2002	Administration of sulpiride to anovulatory mares in winter: effects on prolactin and gonadotropin concentrations, ovarian activity, ovulation and hair shedding.	Sulpiride	18-27	prolactin	Homo sapiens	71-80	
11998830-2	2002	Sulpiride administration increased daily plasma prolactin concentrations (P < 0.05), although the prolactin response during the 6 h following sulpiride injections decreased markedly from the 1st to the 6th day of treatment (treatment by day, P < 0.0001).	Sulpiride	0-9	prolactin	Homo sapiens	48-57	
11998830-2	2002	Sulpiride administration increased daily plasma prolactin concentrations (P < 0.05), although the prolactin response during the 6 h following sulpiride injections decreased markedly from the 1st to the 6th day of treatment (treatment by day, P < 0.0001).	Sulpiride	145-154	prolactin	Homo sapiens	101-110	
11998830-4	2002	Injection of GnRH and TRH on 15 February showed that the response of plasma prolactin to secretagogue was increased in sulpiride-treated mares (P < 0.005), while there was no effect (P > 0.1) of sulpiride treatment on the response of LH or FSH.	Sulpiride	119-128	prolactin	Homo sapiens	76-85	
11998830-4	2002	Injection of GnRH and TRH on 15 February showed that the response of plasma prolactin to secretagogue was increased in sulpiride-treated mares (P < 0.005), while there was no effect (P > 0.1) of sulpiride treatment on the response of LH or FSH.	Sulpiride	201-210	prolactin	Homo sapiens	76-85	
11998830-9	2002	It was concluded that sulpiride administration to seasonally anovulatory mares under the conditions of our experiment increased daily plasma prolactin levels but did not stimulate gonadotropin secretion or ovarian activity.	Sulpiride	22-31	prolactin	Homo sapiens	141-150	
11899856-2	2001	It is noted that sulpiride clearly increases the evolution of prolactin in both sexes.	Sulpiride	17-26	prolactin	Homo sapiens	62-71	
11899856-7	2001	In the article the analysis has been carried out how wider and wider used neuroleptic-sulpiride--influences upon endocrine system and particularly upon the evaluation of prolactin.	Sulpiride	86-95	prolactin	Homo sapiens	170-179	
11418281-6	2001	Significantly higher prolactin levels after sulpiride challenge were however found in depressed patients than controls at all time points after sulpiride administration.	Sulpiride	44-53	prolactin	Homo sapiens	21-30	
11418281-6	2001	Significantly higher prolactin levels after sulpiride challenge were however found in depressed patients than controls at all time points after sulpiride administration.	Sulpiride	144-153	prolactin	Homo sapiens	21-30	
11418281-7	2001	This neuroendocrine challenge paradigm suggests that the prolactin response to sulpiride, a D2 receptor antagonist, is enhanced in depression, which suggests that this receptor might be supersensitive in depression compared to controls.	Sulpiride	79-88	prolactin	Homo sapiens	57-66	
10746297-7	2000	On sulpiride, patients gained weight and exhibited fatigue and increased levels of prolactin.	Sulpiride	3-12	prolactin	Homo sapiens	83-92	
11418281-0	2001	The prolactin response to sulpiride in major depression: the role of the D2 receptor in depression.	Sulpiride	26-35	prolactin	Homo sapiens	4-13	
11418281-2	2001	The aim of the study was to characterise the Dopamine D2 receptor sensitivity status in depressed patients versus controls by means of a novel neuro-endocrine challenge test, the prolactin response to sulpiride.	Sulpiride	201-210	prolactin	Homo sapiens	179-188	
9110224-1	1997	This experiment was designed to determine 1) the efficacy of daily s.c. injections of a dopamine antagonist, sulpiride, for increasing prolactin secretion in geldings in winter and 2) whether increasing prolactin concentrations would hasten the onset of hair shedding or enhance gonadotropin secretion.	Sulpiride	109-118	prolactin	Homo sapiens	135-144	
10505482-14	1999	The laboratory parameters revealed no significant differences between the treatment groups, with the exception of prolactin which moderately exceeded the range of normal in 50% of the patients treated with sulpiride.	Sulpiride	206-215	prolactin	Homo sapiens	114-123	
9110224-5	1997	Over the 8-wk sampling period, prolactin response to sulpiride varied in a quadratic manner (P < .002).	Sulpiride	53-62	prolactin	Homo sapiens	31-40	
9110224-10	1997	In conclusion, even though prolactin concentrations were increased by sulpiride, the effects on gonadotropin secretion and hair shedding were minor and opposite of those expected.	Sulpiride	70-79	prolactin	Homo sapiens	27-36	
9011126-8	1996	The results show that all of the three medicines cause elevation of prolactin level in serum, and sulpiride causes the highest elevation of prolactin level in this study.	Sulpiride	98-107	prolactin	Homo sapiens	140-149	
8904716-3	1996	Prolactin concentrations in plasma were increased by sexual stimulation (P < .01) and sulpiride (P < .001) administration and were decreased (P < .01) when bromocriptine was administered before sexual stimulation.	Sulpiride	89-98	prolactin	Homo sapiens	0-9	
1676524-3	1991	Remoxipride and sulpiride increased the serum levels of prolactin to similar peak levels.	Sulpiride	16-25	prolactin	Homo sapiens	56-65	
7589658-5	1995	MAIN OUTCOME MEASURE: Basal PRL levels and PRL increase induced by sulpiride.	Sulpiride	67-76	prolactin	Homo sapiens	43-46	
7589658-6	1995	RESULTS: Basal PRL levels and the PRL response to sulpiride were increased in women with PCOS.	Sulpiride	50-59	prolactin	Homo sapiens	34-37	
7589658-7	1995	In women with PCOS medical ovariectomy induced by GnRH-a administration reversed to normal both basal and sulpiride-stimulated PRL levels.	Sulpiride	106-115	prolactin	Homo sapiens	127-130	
8329499-0	1993	Prolactin response to sulpiride before and after sleep deprivation in depression.	Sulpiride	22-31	prolactin	Homo sapiens	0-9	
1938655-8	1991	Sulpiride treatment resulted in (P less than .05) a six- to eightfold increase in daily PRL secretion.	Sulpiride	0-9	prolactin	Homo sapiens	88-91	
1938655-9	1991	The PRL response to TRH increased (P less than .05) fourfold in stallions treated with sulpiride but was unchanged in control stallions.	Sulpiride	87-96	prolactin	Homo sapiens	4-7	
1916652-4	1991	After sulpiride administration the incremental area under the PRL profile in PCOS was significantly lower than in normal subjects (p less than 0.01).	Sulpiride	6-15	prolactin	Homo sapiens	62-65	
1676524-5	1991	Sulpiride increased prolactin levels at much lower plasma concentrations than remoxipride, and sulpiride"s effect on prolactin lasted for considerably longer than remoxipride"s.	Sulpiride	0-9	prolactin	Homo sapiens	20-29	
1676524-5	1991	Sulpiride increased prolactin levels at much lower plasma concentrations than remoxipride, and sulpiride"s effect on prolactin lasted for considerably longer than remoxipride"s.	Sulpiride	95-104	prolactin	Homo sapiens	117-126	
2204052-0	1990	[The effect of luliberin and sulpiride on the secretion of gonadotropic hormones and prolactin in patients with obesity].	Sulpiride	29-38	prolactin	Homo sapiens	85-94